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identify the potential partners of STC1 at the protein level, we performed mass spectrometry on B16-F10 tumor cells stably expressing FLAG-tagged STC1.
ORGANISM(S): Mus musculus (Mouse) 
2020-12-23 | PXD023251 | Pride
Evaluation of X-linked gene expression in MEFs isolated from STC1 wild type and knock out mice X chromosome inactivation (XCI) is initiated in cis by the Xist RNA, which coats the inactive X chromosome (Xi) from which it is produced. We performed a large-scale RNA interference screen to identify tr...
ORGANISM(S): Mus musculus 
Oceaniradius stylonematis strain:StC1 Genome sequencing and assembly
Sorafenib is associated with cardiac adverse effects, including left ventricular dysfunction. However, the precise mechanism remains unclear. Here, we aimed to establish the genes responsible for this cardiotoxicity using zebrafish. A pigmentless zebrafish line expressing green fluorescent protein i...
ORGANISM(S): Danio rerio 
Analysis of genes regulated by STC1 down-regulation in mouse 4T1 derived clone, 4T1ch9. STC1 expression is associated with tumor growth and metastasis. This study looks at genes affected when STC1 expression is down-regulated by STC1 shRNA. Total RNA isolated from shRNA transduced cells subjected ...
ORGANISM(S): Mus musculus 
Evaluation of X-linked gene expression in MEFs isolated from STC1 wild type and knock out mice X chromosome inactivation (XCI) is initiated in cis by the Xist RNA, which coats the inactive X chromosome (Xi) from which it is produced. We performed a large-scale RNA interference screen to identify tra...
ORGANISM(S): Mus musculus 
2014-07-29 | GSE47395 | GEO
STC1 promotes temozolomide resistance of glioblastoma through STAT3-mediated regulation of MGMT.
RNA Seq analysis of Mefs Isolated from STC1+/+ and STC1-/- mice
Resistance to temozolomide (TMZ) is one of the major challenges for glioblastoma (GBM) therapy while the underlying mechanisms demand further exploration. Tumor-repopulating cells (TRCs) have been proven to be involved in chemotherapy resistentce. We first enriched GBM TRCs by culturing DBTRG cells ...
ORGANISM(S): Homo sapiens 
2024-04-30 | GSE261684 | GEO
Stc1-expressing myofibroblasts are a developmentally distinct lineage cleared through apoptosis in the neonatal lung
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