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TranscriptomicsAnalyses of Human Brain Metastases of Breast Cancer Reveal the Association between HK2 Up-Regulation and Poor Prognosis
Analyses of Resected Human Brain Metastases of Breast Cancer Reveal the Association between Up-Regulation of Hexokinase 2 and Poor Prognosis. Brain metastases of breast cancer seem to be increasing in incidence as systemic therapy improves. Metastatic disease in the brain is associated with high mor...
ORGANISM(S): Homo sapiens 
2010-01-21 | E-GEOD-20016 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast cancer brain metastases in a mouse xenograft model with vehicle of vorinostat treatment
Gene Expression Profiling of a Mouse Xenograft Model of â??Triple-Negativeâ?? Breast Cancer Brain Metastases With and Without Vorinostat Treatment. Purpose: As chemotherapy and molecular therapy improve the systemic survival of breast cancer patients, the incidence of brain metastases increases. Few...
ORGANISM(S): Homo sapiens 
2009-10-27 | E-GEOD-18544 | biostudies-arrayexpress
TranscriptomicsA BRCA1 Deficient-Like Signature is Enriched in Breast Cancer Brain Metastases
Purpose: There is an unmet clinical need for biomarkers to identify breast cancer patients who are at increased risk of developing brain metastases. The objective is to identify gene signatures and biological pathways associated with HER2+ brain metastasis. Experimental Design: Gene expression of 1...
ORGANISM(S): Homo sapiens 
2014-04-24 | E-GEOD-43837 | biostudies-arrayexpress
TranscriptomicsIdentification and Validation of Genes with Expression Patterns Inverse to Multiple Metastasis Suppressor Genes in Breast Cancer Cell Lines
Metastasis suppressor genes (MSGs) have contributed to an understanding of regulatory pathways unique to the lethal metastatic process. When re-expressed in experimental models, MSGs block cancer spread to, and colonization of distant sites without affecting primary tumor formation. On a single MSG ...
ORGANISM(S): Homo sapiens 
2013-12-27 | E-GEOD-53668 | biostudies-arrayexpress
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