Sort   by:  
 Page size 
UnknownSystematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.
Not available
S-EPMC5695910 | biostudies-literature
UnknownDirect disassembly of α-syn preformed fibrils into α-syn monomers by an all-D-peptide.
Not available
S-EPMC12454639 | biostudies-literature
UnknownPhosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.
Not available
S-EPMC4769169 | biostudies-literature
UnknownA pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.
Not available
S-EPMC6219843 | biostudies-literature
UnknownActivation and Purification of ß-Glucocerebrosidase by Exploiting its Transporter LIMP-2 - Implications for Novel Treatment Strategies in Gaucher's and Parkinson's Disease.
Not available
S-EPMC11220700 | biostudies-literature
UnknownAccurate MS-based Rab10 Phosphorylation Stoichiometry Determination as Readout for LRRK2 Activity in Parkinson's Disease.
Not available
S-EPMC8143643 | biostudies-literature
TranscriptomicsSurface Topography Enhances Differentiation of Mesenchymal Stem Cells Towards Osteogenic and Adipogenic Lineages
Surface topography impacts on cell growth and differentiation, but it is not trivial to generate homogeneous surface structures and to define the specific morphological parameters of relevance. In this study, we have compared gene expression profiles of mesenchymal stem cells (MSCs) on nanostructure...
ORGANISM(S): Homo sapiens 
2015-08-25 | E-GEOD-61113 | biostudies-arrayexpress
GenomicsHigh definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing
DNA methylation stabilizes developmentally programmed gene expression states. Aberrant methylation is associated with disease progression and is a common feature of cancer genomes. Presently, few methods enable quantitative, large-scale, single-base resolution mapping of DNA methylation states in d...
ORGANISM(S): Homo sapiens 
2009-07-08 | E-GEOD-17001 | biostudies-arrayexpress
UnknownDevelopment of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase.
Not available
S-EPMC5748839 | biostudies-literature
TranscriptomicsDominant Th2 differentiation of human regulatory T cells upon loss of FOXP3 expression
CD4+CD25+FOXP3+ regulatory T cells (Treg) are pivotal for peripheral self-tolerance. They prevent immune responses to auto- and alloantigens and are thus under close scrutiny as cellular therapeutics for autoimmune diseases and the prevention or treatment of alloresponses after organ or stem cell tr...
ORGANISM(S): Homo sapiens 
2011-12-14 | E-GEOD-26190 | biostudies-arrayexpress
Sort   by:  
 Page size