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ProteomicsTMT-MS2_cellular adaptation to hypomorphic alleles of essential gene NUP58
Adaptive evolution in response to cellular stress is a critical process implicated in a wide range of core biological and clinical phenomena. Two major routes of adaptation have been identified: non-genetic cellular plasticity, which allows expression of different phenotypes in novel environments, a...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD022255 | Pride
Tmt-ms2 Crispr-cas9 Cellular adaptation Nup58 Essential gene 
UnknownThe unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles.
Not available
S-EPMC4792956 | biostudies-literature
UnknownAssessment of urinary 3-indoxyl sulfate as a marker for gut microbiota diversity and abundance of Clostridiales.
Not available
S-EPMC6546351 | biostudies-literature
UnknownThe lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2.
Not available
S-EPMC9910463 | biostudies-literature
UnknownAge and sex-mediated differences in six-month outcomes after mild traumatic brain injury in young adults: a TRACK-TBI study.
Not available
S-EPMC6571056 | biostudies-literature
GenomicsFoundation Medicine Genomic Data Used to Identify Prognostic Markers and Fusion Genes in Multiple Myeloma
The purpose of this study is to identify prognostic markers and treatment targets using a clinically certified sequencing panel in multiple myeloma. Mutational burden was associated with maf and proliferation gene expression groups, and a high-mutational burden was associated with a poor prognosis....
EGAS00001002874 | EGA
Genomicsena-DATASET-UAMS-09-05-2018-19:35:00:131-1808 - samples
DNA (n=1281) and RNA (n=767) were extracted from bone marrow aspirates where CD138+ selection had been performed to enrich plasma cells from patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), or multiple myeloma (MM). DNA and/or RNA were sent...
EGAD00001004113 | EGA
UnknownLactose drives Enterococcus expansion to promote graft-versus-host disease.
Not available
S-EPMC7003985 | biostudies-literature
UnknownDisease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms.
Not available
S-EPMC12380619 | biostudies-literature
UnknownOverture: an open-source genomics data platform.
Not available
S-EPMC12020472 | biostudies-literature
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