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TranscriptomicsDiscovery of the p53 targetome in MCF7 cells from RNA-seq and ChIP-seq data
This SuperSeries is composed of the SubSeries listed below. iRegulon: from a gene list to a gene regulatory network using large motif and track collections. RekinM-bM-^@M-^Ys Janky, Annelien Verfaillie, Hana ImrichovM-CM-!, Bram Van de Sande, Laura Standaert, Valerie Christiaens, Gert Hulselmans, ...
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-47043 | biostudies-arrayexpress
TranscriptomicsDeregulation of the endogenous C/EBPM-NM-2 LIP isoform predisposes to tumorigenesis
Two long and one truncated isoforms (termed LAP*, LAP, and LIP, respectively) of the transcription factor CCAAT enhancer binding protein beta (C/EBPM-NM-2) are expressed from a single intronless Cebpb gene by alternative translation initiation. Isoform expression is sensitive to mammalian target of ...
ORGANISM(S): Mus musculus 
2014-12-16 | E-GEOD-53770 | biostudies-arrayexpress
TranscriptomicsEffect of PCO1 overexpression [normoxia]
The effect of the overexpression of Plant Cysteine Oxidase (PCO1) on the transcriptome of Arabidopsis rosettes was investigated. For this purpose, 4-week old rosette of wild-type and 35S:FLAG:CDO1 plants were compared. Samples were composed of a pool of 5 plants. In total, 6 samples were analyzes, s...
ORGANISM(S): Arabidopsis thaliana 
2014-02-07 | E-GEOD-44342 | biostudies-arrayexpress
TranscriptomicsEffect of PCO1 overexpression [hypoxia]
The effect of the overexpression of Plant Cysteine Oxidase (PDCO1) on the transcriptome of Arabidopsis resettes was investigated with plants subjected to a 4h hypoxia (5% O2 v/v in air). For this purpose, 4-week old rosette of wild-type and 35S:FLAG:CDO1 plants were compared. Samples were composed ...
ORGANISM(S): Arabidopsis thaliana 
2014-02-07 | E-GEOD-44343 | biostudies-arrayexpress
ProteomicsPreparation of tirapazamine-resistant hepatoma cell line
The aim of the project was to obtain murine hepatoma MH22a [1] cell subline, resistant to anticancer agent 3-amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine, TPZ), and examine the changes of the protein expression as compared with parental cells, with the main emphasis on the changes of redox pr...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD039876 | Pride
Tirapazamine  hepatoma  resistance 
ProteomicsEnhanced interactome capture (eRIC) of steady-state and arsenite stressed HuH7 cell cytoplasmic and nuclear fractions
HuH7 cells were grown under steady-state conditions or exposed 100 µM Na-arsenite for 1h. Subsequently, the cells were irradiated or not with 253 nm UV light (150 mJ/cm^2), processed to nuclear and cytoplasmic fractions, and subjected to eRIC for determining the nuclear and cytoplasmic RNA-binding ...
ORGANISM(S): Homo sapiens (Human) 
2020-04-06 | PXD016735 | Pride
Human Cell culture Arsenite 
TranscriptomicsPesticide and Insect Repellent Mixture (Permethrin and DEET) Induces Epigenetic Transgenerational Inheritance of Disease and Sperm Epimutations
Environmental compounds are known to promote epigenetic transgenerational inheritance of disease. The current study was designed to determine if a M-bM-^@M-^\pesticide mixtureM-bM-^@M-^] (pesticide permethrin and insect repellent N,N-Diethyl-meta-toluamide, DEET) promotes epigenetic transgenerationa...
ORGANISM(S): Rattus norvegicus 
2014-07-22 | E-GEOD-59554 | biostudies-arrayexpress
TranscriptomicsEnvironmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease [NimbleGen]
The actions of environmental toxicants and relevant mixtures in promoting the epigenetic transgenerational inheritance of ovarian disease was investigated with the use of a fungicide, a pesticide mixture, a plastic mixture, dioxin and a hydrocarbon mixture. After transient exposure of an F0 gestatin...
ORGANISM(S): Rattus norvegicus 
2014-07-17 | E-GEOD-59277 | biostudies-arrayexpress
ProteomicsComparative_Interaction_Proteomics_GFP-tagged_MAGEC2_HEK293T
293T (Human embryonic kidney cells-ATCC CRL-3216) cells were plated at 500,000 cells per 10 cm dish and grown for 48 hours. Cells were then transfected with GFP-MAGEC1 WT or GFP-MAGEC1 L318D in a 3:1 ratio of PEI (polyethylenimine) to DNA. Cells were harvested after 48 hours and lysed in 50 mM Tris...
ORGANISM(S): Homo sapiens (Human) 
2024-02-20 | PXD047849 | Pride
Hek293t cells Magec2 Proteomics 
UnknownAzatriangulene-Based Conductive C═C Linked Covalent Organic Frameworks with Near-Infrared Emission.
Not available
S-EPMC11635920 | biostudies-literature
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