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ProteomicsPreparation of tirapazamine-resistant hepatoma cell line
The aim of the project was to obtain murine hepatoma MH22a [1] cell subline, resistant to anticancer agent 3-amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine, TPZ), and examine the changes of the protein expression as compared with parental cells, with the main emphasis on the changes of redox pr...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD039876 | Pride
Tirapazamine  hepatoma  resistance 
UnknownPhase I Dose-Escalation Study of Tirapazamine Chemoembolization for Unresectable Early- and Intermediate-Stage Hepatocellular Carcinoma.
Not available
S-EPMC12483467 | biostudies-literature
UnknownDevelopment and Validation of a Kilogram-Scale Synthesis of Tirapazamine.
Not available
S-EPMC7364547 | biostudies-literature
UnknownElectronic structure and reactivity of tirapazamine as a radiosensitizer.
Not available
S-EPMC8140980 | biostudies-literature
UnknownImproving Tirapazamine (TPZ) to Target and Eradicate Hypoxia Tumors by Gold Nanoparticle Carriers.
Not available
S-EPMC9024542 | biostudies-literature
UnknownRedox Proteomic Profile of Tirapazamine-Resistant Murine Hepatoma Cells.
Not available
S-EPMC10094930 | biostudies-literature
UnknownPhase I Trial on Arterial Embolization with Hypoxia Activated Tirapazamine for Unresectable Hepatocellular Carcinoma.
Not available
S-EPMC8139681 | biostudies-literature
UnknownToward hypoxia-selective DNA-alkylating agents built by grafting nitrogen mustards onto the bioreductively activated, hypoxia-selective DNA-oxidizing agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).
Not available
S-EPMC4136725 | biostudies-literature
UnknownRing-Selective Fragmentation in the Tirapazamine Molecule upon Low-Energy Electron Attachment.
Not available
S-EPMC8003736 | biostudies-literature
UnknownIntroducing urea into tirapazamine derivatives to enhance anticancer therapy.
Not available
S-EPMC10911816 | biostudies-literature
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