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UnknownPhase III study of molecularly targeted adjuvant therapy in locally advanced urothelial cancer of the bladder based on p53 status.
Not available
S-EPMC3164246 | biostudies-literature
GenomicsHistone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes [ChIP-seq]
The molecular signature at histone H3K4 involved in epigenetic regulation of normal (MCF10A) and transformed (MCF7, MDA-MB-231) breast cells using ChIP-Seq technology. This study examines the dynamic distribution of H3K4me3 and H3K4ac histone modification associated with active chromatin to provide...
ORGANISM(S): Homo sapiens 
2016-02-10 | E-GEOD-69377 | biostudies-arrayexpress
TranscriptomicsHistone H3 lysine 4 acetylation-methylation dynamics define breast cancer subtypes [RNA-seq]
The onset and progression of breast cancer are linked to genetic and epigenetic changes that alter the normal programming of cells. Epigenetic modifications of DNA and histones contribute to chromatin structure that results in the activation or repression of gene expression. Several epigenetic pathw...
ORGANISM(S): Homo sapiens 
2016-02-10 | E-GEOD-75168 | biostudies-arrayexpress
TranscriptomicsRUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells.
RUNX1 is a transcription factor functioning both as an oncogene and a tumor suppressor in breast cancer. RUNX1 alters chromatin structure in cooperation with chromatin modifier and remodeling enzymes. In this study, we examined the relationship between RUNX1-mediated transcription and genome organiz...
ORGANISM(S): Homo sapiens 
2016-08-23 | E-GEOD-75070 | biostudies-arrayexpress
GenomicsBivalency - Histone H3 Lysine4 and Histone H3 Lysine27 Methylation Dynamics
The molecular signature at histone H3K4me3 and H3K27me3 involved in epigenetic regulation of normal (MCF10A) and transformed (MCF7, MDA-MB-231) breast cells using ChIP-Seq technology. This study examines the dynamic distribution of H3K4me3, associated with active chromatin, and H3K27me3, associated...
ORGANISM(S): Homo sapiens 
2016-03-24 | E-GEOD-77772 | biostudies-arrayexpress
TranscriptomicsSMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells
The packaging of DNA into chromatin plays an important role in transcriptional regulation and nuclear processes. Brahma related gene-1 SMARCA4 (also known as BRG1), the essential ATPase subunit of the mammalian SWI/SNF chromatin remodeling complex, uses the energy from ATP hydrolysis to disrupt nucl...
ORGANISM(S): Homo sapiens 
2016-06-02 | E-GEOD-74716 | biostudies-arrayexpress
UnknownImpact of centre volume, surgeon volume, surgeon experience and geographic location on reoperation after intramedullary nailing of tibial shaft fractures
Not available
S-EPMC8410470 | biostudies-literature
UnknownElliptic anisotropy measurement of the f<sub>0</sub>(980) hadron in proton-lead collisions and evidence for its quark-antiquark composition.
Not available
S-EPMC12391314 | biostudies-literature
UnknownSearch for supersymmetry in pp collisions at [Formula: see text] TeV in events with a single lepton, jets, and missing transverse momentum.
Not available
S-EPMC4370766 | biostudies-literature
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