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TranscriptomicsActivation of a NCAM1 expressing progenitor cell population in adult human kidney epithelia
NCAM1+ subpopulation of adult human kidney epithelial cells (hKEpC) can be specifically activated in vitro to stem-like cells that de-differentiate and recapitulate embryogenesis. We used microarrays to detail the global programme of gene expression in the NCAM1+ sub-population in comparison to NCAM...
ORGANISM(S): Homo sapiens 
2013-07-23 | E-GEOD-49100 | biostudies-arrayexpress
TranscriptomicsKidney spheroids generate a functional quiescent niche leading to enhanced tubulogenic potency of human kidney-derived cells
Cell-based approaches utilizing autologous human renal cells require their isolation, expansion in vitro and reintroduction back into the host for renal tissue regeneration. Nevertheless, human kidney epithelial cells (hKEpC) lose their phenotype, dedifferentiate and assume the appearance of fibrobl...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-28052 | biostudies-arrayexpress
TranscriptomicsThe Wilms' tumor blastema propagating cell is a self-renewing committed epithelial stem cell
Recently the cancer stem cell (CSC) model has been put forward to describe how a subset of cells within the tumor is responsible for tumor growth and heterogeneity. Wilms' tumor (WT), the most common pediatric renal malignancy, arises from developmentally arrested early renal progenitors. WT NCAM1+A...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-57269 | biostudies-arrayexpress
TranscriptomicsIdentification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease
NCAM1+ subpopulation of fetal human kidneyl cells are nephron progenitors We used microarrays to detail the global programme of gene expression in the NCAM1+ sub-population in comparison to total culture.
ORGANISM(S): Homo sapiens 
2013-07-23 | E-GEOD-49101 | biostudies-arrayexpress
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
UnknownFactors Associated With Large Improvements in Health-Related Quality of Life in Patients With Atrial Fibrillation: Results From ORBIT-AF.
Not available
S-EPMC7247417 | biostudies-literature
UnknownEnhancing cognitive performance prediction by white matter hyperintensity connectivity assessment.
Not available
S-EPMC11629703 | biostudies-literature
UnknownDe novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Not available
S-EPMC7007577 | biostudies-literature
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
UnknownThe National Lung Screening Trial: overview and study design.
Not available
S-EPMC3009383 | biostudies-literature
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