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UnknownVitamin K deficiency bleeding and early infant male circumcision in Africa.
Not available
S-EPMC3773869 | biostudies-literature
UnknownTreatment Patterns, Goals, and Decision-Making Criteria for Second- and Third-Line Therapies for Multiple Myeloma in Germany.
Not available
S-EPMC12313794 | biostudies-literature
TranscriptomicsGene expression changes in U937 cells in response to ectopic expression of EVI1 and/or etoposide treatment
Overexpression of ecotropic viral integration site 1 (EVI1) is associated with aggressive disease in acute myeloid leukemia (AML). Despite of its clinical importance, little is known about the mechanism through which EVI1 confers resistance to antileukemic drugs. Here, we show that a human myeloid c...
ORGANISM(S): Homo sapiens 
2015-03-10 | GSE66660 | GEO
TranscriptomicsGene expression changes in U937 cells in response to ectopic expression of EVI1 and/or etoposide treatment
Overexpression of ecotropic viral integration site 1 (EVI1) is associated with aggressive disease in acute myeloid leukemia (AML). Despite of its clinical importance, little is known about the mechanism through which EVI1 confers resistance to antileukemic drugs. Here, we show that a human myeloid c...
ORGANISM(S): Homo sapiens 
2015-03-10 | E-GEOD-66660 | biostudies-arrayexpress
UnknownIdentification of TFG- and Autophagy-Regulated Proteins and Glycerophospholipids in B Cells.
Not available
S-EPMC11077586 | biostudies-literature
ProteomicsMislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3
Severe forms of dilated cardiomyopathy (DCM) are associated with point mutations in the alternative splicing regulator RBM20 that are frequently located in the arginine/serine-rich domain (RS-domain). Such mutations can cause defective splicing and cytoplasmic mislocalization, which leads to the for...
ORGANISM(S): Homo sapiens (Human) 
2023-06-19 | PXD038790 | Pride
Human Heart Splicing Dilated cardiomyopathy 
UnknownEffectiveness and safety of pegylated filgrastim (Pelgraz®) for the prevention of febrile neutropenia during cancer chemotherapy in all-day practice in Germany.
Not available
S-EPMC12831665 | biostudies-literature
TranscriptomicsThe oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid [U937]
The product of the ecotropic virus integration site 1 (EVI1) gene, whose overexpression is associated with a poor prognosis in myeloid leukemias and some epithelial tumors, regulates gene transcription both through direct DNA binding and through modulation of the activity of other sequence specific ...
ORGANISM(S): Homo sapiens 
2015-03-13 | GSE66854 | GEO
TranscriptomicsSaccharomyces cerevisiae Transcript Isoform mapping
Extensive transcriptional heterogeneity revealed by isoform profiling Application of TIF-Seq (Transcript IsoForm Sequencing) to S.cerevisiae. The method was applied to simultaneously identify the 5' capped mRNA transcription start site and the 3' polyadenylation site in different conditions: WT cell...
ORGANISM(S): Saccharomyces cerevisiae 
2013-05-06 | E-GEOD-39128 | biostudies-arrayexpress
ProteomicsBacterial effector modifies host messenger RNA to promote virulence
Bacterial pathogens harbor specialized secretion systems that inject effector proteins into the host cell toestablish infection and disease. While many bacterial effectors post-translationally modify proteins to influencehost responses, the extent to which effectors modify host RNA is currently unkn...
ORGANISM(S): Homo sapiens (Human) 
2026-08-14 | PXD070774 | Pride
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