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TranscriptomicsChromatin IP of POF, HP1 and H3K9ac and transcript profiling in S2 cells and salivary glands
Two chromosome-targeting and gene regulatory systems are present in Drosophila melanogaster. The male X-chromosome is targeted by the male-specific lethal complex believed to mediate the two-fold up-regulation of the X-linked genes. The highly heterochromatic 4th chromosome is specifically targeted ...
ORGANISM(S): Drosophila melanogaster 
2007-10-02 | E-GEOD-8301 | biostudies-arrayexpress
TranscriptomicsChromatin IP of POF, HP1 and H3K9ac in S2 cells and salivary glands.
Two chromosome-targeting and gene regulatory systems are present in Drosophila melanogaster. The male X-chromosome is targeted by the male-specific lethal complex believed to mediate the two-fold up-regulation of the X-linked genes. The highly heterochromatic 4th chromosome is specifically targeted ...
ORGANISM(S): Drosophila melanogaster 
2007-10-02 | E-GEOD-8296 | biostudies-arrayexpress
TranscriptomicsTranscript profiling in S2 cells and salivary glands.
Two chromosome-targeting and gene regulatory systems are present in Drosophila melanogaster. The male X-chromosome is targeted by the male-specific lethal complex believed to mediate the two-fold up-regulation of the X-linked genes. The highly heterochromatic 4th chromosome is specifically targeted ...
ORGANISM(S): Drosophila melanogaster 
2007-10-02 | E-GEOD-8297 | biostudies-arrayexpress
GenomicsDorsal dependent CBP binding on a genome wide scale
We find a high concordance between the binding of the Drosophila transcription factor Dorsal and the co-activator CBP during early embryogenesis. This relationship was furter examined by comparing CBP distribution in Drosophila embryos derived from wt and mutant flies lacking intranuclear Dorsal (gd...
ORGANISM(S): Drosophila melanogaster 
2012-06-28 | E-GEOD-34221 | biostudies-arrayexpress
TranscriptomicsHP1a recruitment to promoters is independent of H3K9 methylation in Drosophila melanogaster
Heterochromatin protein 1 (HP1) proteins are important regulators of heterochromatin mediated gene silencing and chromosome structure and it is well known as the reader of the heterochromatin mark methylation of histone H3 lysine 9 (H3K9me). In Drosophila three different histone lysine methyl transf...
ORGANISM(S): Drosophila melanogaster 
2012-12-21 | E-GEOD-38366 | biostudies-arrayexpress
TranscriptomicsBuffering and proteolysis are induced upon segmental haploidy in Drosophila melanogaster.
Aneuploidy, i.e., variation in the number of individual chromosomes (chromosomal aneuploidy) or chromosome segment (segmental aneuploidy) is associated with developmental abnormalities and reduced fitness in all species examined, is the leading cause of miscarriages and mental retardations and a hal...
ORGANISM(S): Drosophila melanogaster 
2012-04-04 | E-GEOD-34400 | biostudies-arrayexpress
TranscriptomicsHP1a, Su(var)3-9, SETDB1 and POF stimulate or repress gene expression depending on genomic position, gene length and expression pattern in Drosophila melanogaster
Heterochromatin protein 1a (HP1a) is a chromatin associated protein that has been well studied in many model organisms, such as Drosophila, where it is a determining factor for classical heterochromatin. HP1a is associated with the two histone methyltransferases SETDB1 and Su(var)3-9, which mediate ...
ORGANISM(S): Drosophila melanogaster 
2013-04-05 | E-GEOD-43478 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of wild type and Pof mutant Drosophila melanogaster females
In Drosophila, two chromosome-wide compensatory systems have been characterized; the dosage compensation system acting on the male X-chromosome and the chromosome specific regulation of genes located on the heterochromatic 4th chromosome. Dosage compensation in Drosophila is accomplished by hypertra...
ORGANISM(S): Drosophila melanogaster 
2012-05-30 | E-GEOD-28513 | biostudies-arrayexpress
UnknownSafety of bariatric surgery in patients with previous acute coronary events or heart failure: nationwide cohort study.
Not available
S-EPMC9177412 | biostudies-literature
UnknownComparison of Sleeve Gastrectomy vs Intensive Lifestyle Modification in Patients With a BMI of 30 to Less Than 35.
Not available
S-EPMC9331100 | biostudies-literature
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