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Modulation of the human pancreatic ductal adenocarcinoma immune microenvironment by stereotactic body radiotherapy
Immune checkpoint inhibitor (ICI) resistance in advanced hepatocellular carcinoma (HCC)poses a major therapeutic challenge. Here, we report a phase 2 trial evaluating stereotactic bodyradiotherapy (SBRT) combined with the anti-PD-1 antibody sintilimab and bevacizumabbiosimilar (lBI305) to re-sensiti...
ORGANISM(S): Homo sapiens (Human) 
2025-10-15 | PAD000004 | Pride
A Prospective Pilot Study of Urine microRNA as a Biomarker of Urinary Toxicity Following MRI-Guided Prostate Stereotactic Body Radiotherapy
Background and purpose: To directly reveal the change in genome mutation, RNA transcript of tumor cells, and tumor microenvironment (TME) after stereotactic body radiotherapy (SBRT) in paired human lung tumor specimens.
ORGANISM(S): Homo sapiens 
2020-12-10 | GSE162944 | GEO
Background and purpose: To directly reveal the change in genome mutation, RNA transcript of tumor cells, and tumor microenvironment (TME) after stereotactic body radiotherapy (SBRT) in paired human lung tumor specimens.
ORGANISM(S): Homo sapiens 
2020-12-10 | GSE162945 | GEO
Purpose: Stereotactic body radiotherapy (SBRT) is an emerging treatment modality for pancreatic ductal adenocarcinoma (PDAC) that can effectively prime cytotoxic T cells by inducing immunogenic tumor cell death in preclinical models. SBRT effects on human PDAC have yet to be thoroughly investigated,...
ORGANISM(S): Homo sapiens 
2021-10-08 | GSE185311 | GEO
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