Sort   by:  
 Page size 
TranscriptomicsAnalyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphoma
The pathogenesis of classical Hodgkin lymphoma (cHL), the most common lymphoma in the young, is still enigmatic, largely because its Hodgkin and Reed-Sternberg (HRS) tumor cells are rare in the involved lymph node and therefore difficult to analyze. Here, by overcoming this technical challenge and p...
ORGANISM(S): Homo sapiens 
2012-09-17 | E-GEOD-40160 | biostudies-arrayexpress
TranscriptomicsExpression data from Hodgkin lymphoma cell lines UHO-1 and L-1236 transduced with shRNAs against GATA-3 or non-functional control shRNAs
The transcription factor network in Hodgkin lymphoma (HL) represents a unique composition of proteins found in no other hematopoietic cell. Among these factors, an aberrant expression of the T cell transcription factor GATA-3 is observed in the B cell-derived Hodgkin and Reed/Sternberg (HRS) tumor c...
ORGANISM(S): Homo sapiens 
2010-07-24 | E-GEOD-22550 | biostudies-arrayexpress
TranscriptomicsThe genome and transcriptome of Panagrellus redivivus is shaped by the harsh demands of a free-living lifestyle
Nematodes comprise an abundant and diverse invertebrate phylum with members inhabiting nearly every ecological niche. Panagrellus redivivus (the M-bM-^@M-^YmicrowormM-bM-^@M-^Y) is a free-living nematode frequently used to understand the evolution of developmental and behavioral processes given its ...
ORGANISM(S): Panagrellus redivivus 
2013-02-07 | E-GEOD-44020 | biostudies-arrayexpress
UnknownIdentification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profiling.
Not available
S-EPMC151925 | biostudies-literature
UnknownA conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function.
Not available
S-EPMC2683036 | biostudies-literature
TranscriptomicsExpression study of the Hodgkin’s lymphoma cell line L-1236 upon CRISPR Cas9-mediated knockout of lymphotoxin alpha (LTA) compared to control
Persistent activation of canonical and non-canonical NF-κB pathways is a hallmark of the malignant Hodgkin and Reed-Sternberg cells in classical Hodgkin lymphoma (cHL). We identified lymphotoxin alpha (LTA), which is secreted by the cHL cell line L-1236 in high concentrations. This cytokine contribu...
ORGANISM(S): Homo sapiens 
2019-01-24 | E-MTAB-6896 | biostudies-arrayexpress
GenomicsChIP-Seq of RNA Pol II with antibodies S2, 4H8 and 8WG16 during C. elegans L1 arrest and recovery
When C. elegans larvae hatch in the absence of food they persist in a stress resistant, developmentally arrested state (L1 arrest) for weeks or until food becomes available. We characterized growth, mRNA expression, and RNA Polymerase II activity genome-wide during L1 arrest and recovery. RNA Pol ...
ORGANISM(S): Caenorhabditis elegans 
2009-02-27 | E-GEOD-13973 | biostudies-arrayexpress
UnknownNeural similarity across task load relates to cognitive reserve and brain maintenance measures on the Letter Sternberg task: a longitudinal study.
Not available
S-EPMC9925407 | biostudies-literature
UnknownDeep Sequencing of Immunoglobulin Genes Identifies a Very Low Percentage of Monoclonal B Cells in Primary Cutaneous Marginal Zone Lymphomas with CD30-Positive Hodgkin/Reed-Sternberg-like Cells.
Not available
S-EPMC8870847 | biostudies-literature
UnknownGenomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion.
Not available
S-EPMC6963251 | biostudies-literature
Sort   by:  
 Page size