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TranscriptomicsPersistence of Smoking-induced Dysregulation of Small Airway Epithelium miRNA Expression Despite Smoking Cessation
Rationale: Even after quitting smoking, the risk of the development of chronic obstructive pulmonary disease (COPD) and lung cancer remains significantly higher compared to never-smokers. Objectives: Based on the knowledge that COPD and most lung cancers start in the small airway epithelium (SAE), w...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-53519 | biostudies-arrayexpress
TranscriptomicsAltered Expression of Intraflagellar Transport Genes is Associated with Short Cilia in Smoking and COPD
Study Smoking and COPD are associated with decreased mucociliary clearance and healthy smokers have shorter cilia in the large airway than nonsmokers. Intraflagellar transport (IFT) is the process by which cilia are produced and maintained. We assessed expression of IFT-related genes in smokers and ...
ORGANISM(S): Homo sapiens 
2014-02-03 | E-GEOD-43939 | biostudies-arrayexpress
TranscriptomicsBP1 Expression Promotes Tumorigenesis and Aggression in MCF-7 Breast Cancer Cells
This study was designed to identify genes that are differentially expressed when BP1 homeobox gene is overexpressed in MCF-7 breast cancer cells. The goal is to understand the functional role of BP1 in breast tumorigenesis. MCF-7 overexpressing pcDNA3.2-BP1 clones, O1 and O4 as replicates vs. MCF-7 ...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21657 | biostudies-arrayexpress
Unknown2023 Canadian Surgery Forum: Sept. 20-23, 2023.
Not available
S-EPMC10718225 | biostudies-literature
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