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ProteomicsMass spectrometry analysis of proteins interacting with STING mutants
To investigate proteins interacting with STING mutants, HEK 293T cells were co-transfected with three STING mutant expression plasmids (human STING WT, STING delCTT (aa343-379 deletion), STING del6 (aa325-379 deletion) in a pcDNA3.1+ backbone) and either pcDNA-cGAS expression plasmid or control empt...
ORGANISM(S): Homo sapiens (Human) 
2024-02-19 | PXD038063 | Pride
Sting mutants Hek 293t Sting-interacting proteins Lc-ms/ms 
UnknownAfrican Swine Fever Virus Structural Protein p17 Inhibits cGAS-STING Signaling Pathway Through Interacting With STING.
Not available
S-EPMC9283692 | biostudies-literature
UnknownCharacteristic Analysis of Ictalurus punctatus STING and Screening Validation of Interacting Proteins with Ictalurid herpesvirus 1
Not available
S-EPMC12388441 | biostudies-literature
ProteomicsBJ Flag-STING IP Mass Spectrometry
The goal of this project is to identify interacting proteins of Flag-tagged STING before and after cGAMP stimulation. STING knockout (STING-KO) BJ cells stably re-expressing Flag-STING were treated with 1 M cGAMP and whole cell lysates were harvested 30 min later for IP with anti-Flag M2 affinity ge...
ORGANISM(S): Homo sapiens (Human) 
2025-12-07 | PXD059426 | Pride
Immunoprecipitation Sting Cgamp 
TranscriptomicsVreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila
In Drosophila, Piwi proteins associate with Piwi-interacting RNAs (piRNAs) and protect the germline genome by silencing mobile genetic elements. This defense system acts in germline and gonadal somatic tissue to preserve germline development. Genetic control for these silencing pathways varies great...
ORGANISM(S): Drosophila melanogaster 
2011-09-28 | E-GEOD-30360 | biostudies-arrayexpress
TranscriptomicsVreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila.
Here, we analyzed small RNA libraries derived from ovarian tissues heterozygous or mutant for the Tudor gene, Vreteno. In the absence of vret, Piwi-bound piRNAs are lost without changes in piRNA precursor transcript production, supporting a role for Vret in primary piRNA biogenesis. In the germline,...
ORGANISM(S): Drosophila melanogaster 
2011-08-15 | E-GEOD-30088 | biostudies-arrayexpress
UnknownAfrican swine fever virus MGF505-6R attenuates type I interferon production by targeting STING for degradation.
Not available
S-EPMC11116646 | biostudies-literature
UnknownSTING-induced noncanonical autophagy regulates endolysosomal homeostasis.
Not available
S-EPMC11874320 | biostudies-literature
UnknownSAM68 directs STING signaling to apoptosis in macrophages.
Not available
S-EPMC10920828 | biostudies-literature
UnknownModulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses.
Not available
S-EPMC4534226 | biostudies-literature
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