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TranscriptomicsTraf6 function in the innate immune response of zebrafish embryos
Transcriptional profiling of the zebrafish embryonic host response to a systemic bacterial infection with Salmonella typhimurium (strain SL1027); comparison between traf6 knock-down and control morpholino treated embryos. All infection experiments were performed using mixed egg clutches of ABxTL str...
ORGANISM(S): Danio rerio 
2010-08-01 | E-GEOD-21024 | biostudies-arrayexpress
TranscriptomicsSalmonella typhimurium infection of zebrafish embryo
Characterization of the zebrafish embryonic host response to systemic bacterial infection with Salmonella typhimurium wild type strain (SL1027) and its isogenic LPS O-antigen mutant Ra (SF1592) by means of a time-resolved global expression analysis. All infection experiments were performed using mix...
ORGANISM(S): Danio rerio 
2010-05-22 | E-GEOD-13994 | biostudies-arrayexpress
TranscriptomicsMacrophage-specific gene functions in Spi1-directed innate immunity
The Spi1/ Pu.1 transcription factor plays a crucial role in myeloid cell development across many species. Several Spi1 target genes have been identified so far, yet the Spi1-dependent gene group remains largely unknown. To identify novel genes downstream of Spi1 we employed a microarray strategy usi...
ORGANISM(S): Danio rerio 
2010-04-30 | E-GEOD-19206 | biostudies-arrayexpress
TranscriptomicsDeep sequencing of the innate immune transcriptomic response of zebrafish embryos to Salmonella infection
Salmonella enterica serovar Typhimurium (S. typhimurium) bacteria cause an inflammatory and lethal infection in zebrafish embryos. To characterize the embryonic innate host response at the transcriptome level, we have extended and validated previous microarray data by Illumina next-generation sequen...
ORGANISM(S): Danio rerio 
2010-10-25 | E-GEOD-22472 | biostudies-arrayexpress
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