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TranscriptomicsA Gene Expression Signature for Insulin Resistance
Insulin resistance is a heterogeneous disorder caused by a range of genetic and environmental factors, and we hypothesise that its aetiology varies considerably between individuals. This heterogeneity provides significant challenges to the development of effective therapeutic regimes for long-term m...
ORGANISM(S): Mus musculus 
2010-09-10 | E-GEOD-18103 | biostudies-arrayexpress
TranscriptomicsEstablishment of photosynthesis through chloroplast development is controlled by two distinct regulatory phases
A pluripotent inducible cell line was generated from Arabidopsis to address the limitations of traditional in planta dicot systems and to develop a well-controlled experimental setup where the individual regulatory check points of chloroplast development could be defined. Following light exposure, t...
ORGANISM(S): Arabidopsis thaliana 
2018-05-12 | E-MTAB-5777 | biostudies-arrayexpress
UnknownStrand 6B deformation and residues exposure towards N-terminal end of helix B during proteinase inhibition by Serpins.
Not available
S-EPMC3046034 | biostudies-literature
TranscriptomicsDNA intermediates of meiotic recombination in synchronous S. pombe at optimal temperature
Crossovers formed by recombination between homologous chromosomes are important for proper homolog segregation during meiosis and for generation of genetic diversity. Optimal molecular analysis of DNA intermediates of recombination requires synchronous cultures. We previously described a mutant, p...
ORGANISM(S): Schizosaccharomyces pombe 
2013-09-20 | E-GEOD-49961 | biostudies-arrayexpress
UnknownDNA-Dependent Protein Kinase Catalytic Subunit: The Sensor for DNA Double-Strand Breaks Structurally and Functionally Related to Ataxia Telangiectasia Mutated.
Not available
S-EPMC8394720 | biostudies-literature
UnknownGrowth Performance, Nutrient Digestibility, and Retention in Atlantic Salmon, Salmo salar L., Fed Diets with Fermented Sugar Kelp, Saccharina latissima.
Not available
S-EPMC10699978 | biostudies-literature
TranscriptomicsRNA Sequencing of miR-10b +/+ and miR-10b -/- Mouse Embryonic Stem Cells During Adipocyte Differentiation at Days 0, 12, and 27
The experiment was designed to investigate the sequence of events regulating preadipocyte commitment and terminal differentiation into adipocytes, providing insight into brown fat physiology and metabolic dysfunction. miR-10b was found to be upregulated in brown adipocytes, and CRISPR/Cas9 was used ...
ORGANISM(S): Mus musculus 
2026-05-01 | E-MTAB-15151 | biostudies-arrayexpress
TranscriptomicsaSyn polyA-RNAseq in PD and unaffected cortical brain samples
We sought to more precisely characterize the different alpha-synuclein (aSyn) 3M-bM-^@M-^YUTR mRNA species in normal and PD human brain. High-throughput, whole-transcriptome sequencing of the 3M-bM-^@M-^YUTR ends of polyadenylated mRNA transcripts (termed pA-RNAseq; see Methods) was performed on a ...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-GEOD-40710 | biostudies-arrayexpress
UnknownFunctional analysis of XRCC4 mutations in reported microcephaly and growth defect patients in terms of radiosensitivity.
Not available
S-EPMC8127669 | biostudies-literature
UnknownFour SNPs in the untranslated region of the NOTCH2 gene involved in reproductive traits in fertile and anestrum Holstein Friesian cattle.
Not available
S-EPMC11681750 | biostudies-literature
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