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The incidence of esophageal and junctional adenocarcinoma has increased 6 fold in the last 30 years and 5 year survival remains less than 14%. Once considered an inert scaffold, the stromal compartment is now recognized to play a central role in invasive cancer. However, whether the stroma plays a r...
ORGANISM(S): Homo sapiens 
scATACseq of sorted stromal cell compartment from patients with Crohn's disease
scRNAseq of sorted stromal cell compartment from patients with Crohn's disease
Progesterone regulated genes in the endometrial stromal compartment were studied in proven fertile women using laser dissection capture microscopy followed by microarray. Endometrial biopsies were obtained from women before (control group, n=9) and after (study group, n=9) treatment with mifepriston...
ORGANISM(S): Homo sapiens 
Comparison of gene expression in the stromal cell compartment (Lineage negative, CD45 negative bone marrow cells) of C57B/L6 and B6.SJL (Ly5.1) mice. duplicate samples were analyzed per strain (two biological replicates) and each of the two samples was pooled from 5 mice
ORGANISM(S): Mus musculus 
The tumor microenvironment plays a critical role in cancer progression, but the precise mechanisms by which stromal cells influence the tumor epithelium are poorly understood. The signaling adapter p62 has been implicated as a positive regulator of epithelial tumorigenesis; however, its role in the ...
ORGANISM(S): Mus musculus 
A single cell transcriptome atlas of Human thymic stromal compartment
Azacitidine Modulates the Mesenchymal Stromal Cell Compartment in Myelodysplastic Syndromes
Stromal support is critical to the achievement of lung homeostasis and the maintenance of an effective epithelial barrier, and yet previous studies have found a positive association between the number of mesenchymal stromal cell populations (MSCs) isolated from the alveolar space and human diseases ...
ORGANISM(S): Homo sapiens 
In the bone marrow B cell development occurs in initimate and essential association with stromal cells. Known effects of stromal cells on B cell development have been shown to be mediated through direct contact and by soluble factors produced by stromal cells. Our findings suggest that cell-nonauto...
ORGANISM(S): Mus musculus 
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