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TranscriptomicsComparison of steady state mRNA levels between equine articular cartilage and ten other equine tissues
A tissue survey of gene expression was conducted using microarray-based transcriptional profiling to compare equine articular cartilage to 10 other normal adult horse tissues. The ten comparative tissues were bladder, cerebellum, kidney, liver, lung, lymph node, muscle, placental villous, spleen, a...
ORGANISM(S): Equus caballus 
2011-01-27 | E-GEOD-23862 | biostudies-arrayexpress
UnknownA probabilistic method for leveraging functional annotations to enhance estimation of the temporal order of pathway mutations during carcinogenesis.

Background

Cancer arises through accumulation of somatically acquired genetic mutations. An important question is to delineate the temporal order of somatic mutations during carcinogenesis, which contributes to better understanding of cancer biology and facilitates identification of new ther...
S-EPMC6889196 | biostudies-literature
UnknownReduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk.

Rationale

Former smoking history and chronic obstructive pulmonary disease (COPD) are potential risk factors for osteoporosis and fractures. Under existing guidelines for osteoporosis screening, women are included but men are not, and only current smoking is considered.

Objectives

To ...
S-EPMC4418341 | biostudies-literature
UnknownDeep learning enhanced ALPS reveals genetic and environmental factors of brain glymphatic function.

Background

The glymphatic system plays a critical role in brain waste clearance and health. Diffusion tensor imaging along the perivascular space (DTI-ALPS) is an emerging approach to assess glymphatic function, but manual analysis is limited by its subjectivity and laboriousness in clinical...
S-EPMC12878677 | biostudies-literature
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