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TranscriptomicsDigital RNA Sequencing Minimizes Sequence-Dependent Bias and Amplification Noise with Optimized Single Molecule Barcodes
RNA-Seq is a powerful tool for transcriptome profiling, but is hampered by sequence-dependent bias and inaccuracy at low copy numbers intrinsic to exponential PCR amplification. We developed a simple strategy for mitigating these complications, allowing truly digital RNA-Seq. Following reverse tra...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2012-01-07 | E-GEOD-34449 | biostudies-arrayexpress
UnknownRobust Carbonated Structural Color Barcodes with Ultralow Ontology Fluorescence as Biomimic Culture Platform.
Not available
S-EPMC8118130 | biostudies-literature
UnknownDetection of structural variations in densely-labelled optical DNA barcodes: A hidden Markov model approach.
Not available
S-EPMC8570516 | biostudies-literature
UnknownHydroxypropyl Cellulose Assembled Microspheres as Structural Color Barcodes from Revolving Microfluidics.
Not available
S-EPMC12407317 | biostudies-literature
GenomicsDesign and Assembly of Combinatorial DNA Barcodes for Probe-based Genomics Applications
Design and Assembly of Combinatorial DNA Barcodes for Probe-based Genomics Applications
PRJNA1532771 | ENA
UnknownPollen-Inspired Photonic Barcodes with Prickly Surface for Multiplex Exosome Capturing and Screening.
Not available
S-EPMC9470204 | biostudies-literature
OtherDesign and Assembly of Combinatorial DNA Barcodes for Probe-based Genomics Applications
Probe-based genomics technologies are extending molecular analysis into intact tissues and fixed cells, yet strategies to decode complex experimental conditions encoded in cellular RNA remain limited. Here we present a modular framework that integrates custom software tools with purposebuilt cloning...
ORGANISM(S): synthetic construct 
2026-09-23 | GSE348054 | GEO
TranscriptomicsProbing nucleosome function: A highly versatile library of synthetic histone H3 and H4 mutants
The structural integrity of the nucleosome is central to regulation of DNA metabolism and transcription. We describe a library of 486 systematic histone H3 and H4 substitution and deletion mutants in Saccharomyces cerevisiae that probe the contribution of each residue to nucleosome function and can ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-09-18 | E-GEOD-10860 | biostudies-arrayexpress
UnknownCovert thermal barcodes based on phase change nanoparticles.
Not available
S-EPMC4046349 | biostudies-literature
OtherDesign and Assembly of Combinatorial DNA Barcodes for Probe-based Genomics Applications [Pyxa spatial transcriptomic]
Probe-based genomics technologies are extending molecular analysis into intact tissues and fixed cells, yet strategies to decode complex experimental conditions encoded in cellular RNA remain limited. Here we present a modular framework that integrates custom software tools with purposebuilt cloning...
ORGANISM(S): Mus Mus musculus 
2026-09-26 | GSE348619 | GEO
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