In the project “Proteome dynamics in retinal development” by Juan Zapata Munoz, Michael Stumpe, Joern Dengjel, and Patricia Boya, we performed expression proteomics of mouse retinas.
Study of the protein composition of the trophallactic fluid of the carpenter ant Camponotus floridanus. Samples were analyzed from ants with different functions (Nurse, Forager) coming from colonies with different ages (mature, young) either kept in lab or grown under natural conditions.
In symbiotic plant-microbe interactions, the host invests considerable amounts of resources in the microbial partner. If the microbe does not reciprocate with a comparable symbiotic benefit it is regarded as a cheater. The host responds to cheaters with negative feedback mechanisms (sanctions) to pr...
In eukaryotes, most newly synthesized ribosomal proteins (r-proteins) need to rapidly and safely get into the nucleus to reach their assembly site on pre-ribosomal particles. However, only for few r-proteins tailored support mechanisms involving so-called dedicated chaperones could so far be reveale...
Eukaryotic ribosome synthesis is a highly complex, multistep process that is best characterized in the yeast Saccharomyces cerevisiae. It is orchestrated by over 200 ribosome assembly factors and 75 small nucleolar ribonucleoproteins (snoRNPs), which guide site-specific chemical modifications of pre...
In eukaryotes, most newly synthesized ribosomal proteins (r-proteins) need to rapidly and safely get into the nucleus to reach their assembly site on pre-ribosomal particles. However, only for few r-proteins tailored support mechanisms involving so-called dedicated chaperones could so far be reveale...
Four sets of MS-based proteomics experiments were performed: (1) Serine/Threonine protein phosphatases were profiled by microcystin-LR (MCLR)-based enrichment in different growth conditions; (2) TurboID-RTS3-based proximity labeling was performed to characterize the RTS3 protein neighborhood; (3) A...
In symbiotic plant-microbe interactions, the host invests considerable amounts of resources in the microbial partner. If the microbe does not reciprocate with a comparable symbiotic benefit it is regarded as a cheater. The host responds to cheaters with negative feedback mechanisms (sanctions) to pr...
In symbiotic plant-microbe interactions, the host invests considerable amounts of resources in the microbial partner. If the microbe does not reciprocate with a comparable symbiotic benefit it is regarded as a cheater. The host responds to cheaters with negative feedback mechanisms (sanctions) to pr...
Intrinsically disordered regions (IDRs) are highly enriched in the nucleolar proteome but their physiological role in ribosome assembly remains poorly understood. Our study reveals the functional plasticity of the extremely abundant lysine-rich IDRs of small nucleolar ribonucleoprotein particles (sn...
