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GenomicsTissue- and Stage-specific ChIP for H3K27ac, CTCF, Beaf and Su(Hw) in D. melanogaster embryos
This study contains a series of ChIP-seq experiments performed on nuclear material similar to what was used in Tissue- and Stage-specific Capture-C for selected TSS and CRM (BioStudies/ArrayExpress collection E-MTAB-9310). ChIP-seq with chromatin isolated from nuclei isolated from 2-3h whole embryos...
ORGANISM(S): Drosophila melanogaster 
2023-06-30 | E-MTAB-12639 | biostudies-arrayexpress
UnknownThe non-apoptotic action of Bcl-xL: regulating Ca(2+) signaling and bioenergetics at the ER-mitochondrion interface.
Not available
S-EPMC6737942 | biostudies-literature
TranscriptomicsSecreted Frizzled-Related Protein 5 is Downregulated in Obesity and Promotes β-Cell Proliferation [10 days]
Obesity is associated with an increase in β-cell mass in response to the rising demand for insulin. β-cell plasticity is essential to maintaining glucose homeostasis, however, the cellular and molecular mechanisms by which β-cell mass is regulated remain poorly understood. Recently, we described the...
ORGANISM(S): Rattus norvegicus 
2014-10-10 | E-GEOD-44045 | biostudies-arrayexpress
TranscriptomicsSecreted Frizzled-Related Protein 5 is Downregulated in Obesity and Promotes ?-Cell Proliferation [30 days]
Obesity is associated with an increase in ?-cell mass in response to the rising demand for insulin. ?-cell plasticity is essential to maintaining glucose homeostasis, however, the cellular and molecular mechanisms by which ?-cell mass is regulated remain poorly understood. Recently, we described the...
ORGANISM(S): Rattus norvegicus 
2014-10-10 | E-GEOD-44046 | biostudies-arrayexpress
TranscriptomicsMethamphetamine administration causes differential alterations in gene expression and dynamic patterns of histone acetylation/hypoacetylation in the rat nucleus accumbens
Methamphetamine (METH) addiction is associated with a plethora of neuropsychiatric symptoms. In rodents, administration of the drug is accompanied by complex changes in gene expression in the dorsal striatum. Very little is known about the effects of the drug on gene expression and epigenetic modifi...
ORGANISM(S): Rattus norvegicus 
2011-07-31 | E-GEOD-31081 | biostudies-arrayexpress
TranscriptomicsRERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer
Using microarray analysis, we identified a unique ras superfamily gene, termed RERG (ras-related and estrogen-regulated growth inhibitor), whose expression was decreased or lost in a significant percentage of primary human breast tumors that show a poor clinical prognosis. Importantly, high RERG exp...
ORGANISM(S): Homo sapiens 
2005-07-23 | E-GEOD-2987 | biostudies-arrayexpress
ProteomicsHuman exosome proteome - Human urinary exosomes as innate immune effectors
Proteomics study of human urine exosomes. This data describes the proteomic complement of the human exosomal urine fraction from 10 healthy volunteers (5 male, 5 female) aged 23 to 36 years. 50 µg protein from each sample were fragmented on a 4%/12% SDS-polyacrylamide gel. Following staining, each g...
ORGANISM(S): Homo sapiens (Human) 
2016-08-25 | PXD000117 | Pride
Exosome Urine Human Proteome 
TranscriptomicsEvaluation of gene expression data generated from expired Affymetrix GeneChip® microarrays using MAQC reference RNA samples
The Affymetrix GeneChip® system is a commonly used platform for microarray analysis but the technology is inherently expensive. Unfortunately, changes in experimental planning and execution, such as the unavailability of previously anticipated samples or a shift in research focus, may render signifi...
ORGANISM(S): Homo sapiens 
2010-09-02 | E-GEOD-23906 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse brain from animals treated with cocaine vs controls
Several recent reports show that the cerebral cortex in humans and animals with altered expressions of Wnt/cadherin network-associate molecules display cytoarchitectural abnormalities reminiscent of cortical dysplasias seen in some (mouse-, rat-, and monkey-based) animal models of prenatal cocaine e...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6628 | biostudies-arrayexpress
UnknownDevelopment and validation of a potent and specific inhibitor for the CLC-2 chloride channel.
Not available
S-EPMC7768775 | biostudies-literature
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