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We employed a massively parallel, high resolution Capture-C based method to simultaneously characterize the genome-wide interactions of all human promoters in any cell type. We applied this approach to study the promoter interactome of HepG2 cells (3 biological replicates). We designed a custom Agil...
ORGANISM(S): Homo sapiens 
Comparing gene expressing profile of human embryonic stem cells and neuroepithelial cells differentiated from human embryonic stem cells.
ORGANISM(S): Homo sapiens 
To connect the neuronal developmental disorders associated GWAS signal to their target effector genes, we performed an integrated analysis of transcriptomics, epigenomics and chromatin conformation changes in an in vitro cellular model. Induced human pluripotent stem cell–derived neural progenitor c...
ORGANISM(S): Homo sapiens 
NIH3T3 cells were cultured in medium containing 1 uM, 100 nM, 10 nM and 0 nM (serve as control) shld1 for 24 hours. Three independent cultures were obtained for each drug concentration. Total RNA from experimental samples were extracted using RNeasy Kit (Qiagen). Mouse RNA pooled from 11 cell line...
ORGANISM(S): Mus musculus 
Evaluation of gene transcripts that are downstream of apelin/APJ signaling in HUVECs Duplicates per group, subjected to: 1) control siRNA, 2) MEF2A and MEF2C siRNA, 3) G alpha 13 siRNA, and 4) apelin and APJ siRNA
ORGANISM(S): Homo sapiens 
To connect the neuronal developmental disorders associated GWAS signal to their target effector genes, we performed an integrated analysis of transcriptomics, epigenomics and chromatin conformation changes in an in vitro cellular model. Induced human pluripotent stem cell–derived neural progenitor c...
ORGANISM(S): Homo sapiens 
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