Sort   by:  
 Page size 
GenomicsNOTCH1/RBPJ complexes drive target gene expression through dynamic interactions with super-enhancers
The main oncogenic driver in T-lymphoblastic leukemia (T-LL) is NOTCH1, which activates genes by forming chromatin-associated Notch transcription complexes. Gamma-secretase (GSI) inhibitor treatment prevents NOTCH1 nuclear localization, but most genes with NOTCH1 binding sites are insensitive to GSI...
ORGANISM(S): Homo sapiens 
2013-12-27 | E-GEOD-51800 | biostudies-arrayexpress
GenomicsGenome-wide Analysis Reveals Conserved and Divergent Features of Notch1/RBPJ Binding in Human and Murine T Lymphoblastic Leukemia Cells
Notch1 regulates gene expression by associating with the DNA-binding factor RBPJ and is oncogenic in murine and human T cell progenitors. Using ChIP-Seq, we find that in human and murine T-LL genomes Notch1 binds preferentially to promoters, to RBPJ binding sites, and near imputed ZNF143, Ets and Ru...
ORGANISM(S): Mus musculus 
2011-07-06 | E-GEOD-29600 | biostudies-arrayexpress
UnknownPersonalization and localization as key expectations of digital health intervention in women pre- to post-pregnancy.
Not available
S-EPMC10541409 | biostudies-literature
UnknownAntenatal education and postnatal support strategies for improving rates of exclusive breast feeding: randomised controlled trial.
Not available
S-EPMC1989016 | biostudies-literature
UnknownAlginate Oligosaccharide Prevents Acute Doxorubicin Cardiotoxicity by Suppressing Oxidative Stress and Endoplasmic Reticulum-Mediated Apoptosis.
Not available
S-EPMC5192468 | biostudies-literature
UnknownShaping Adoption and Sustained Use Across the Maternal Journey: Qualitative Study on Perceived Usability and Credibility in Digital Health Tools.
Not available
S-EPMC11480679 | biostudies-literature
UnknownIncreased Risk of Osteoporosis in Patients With Peptic Ulcer Disease: A Nationwide Population-Based Study.
Not available
S-EPMC4845819 | biostudies-literature
UnknownPreconception maternal retinal venular widening and steeper resistance increments in the utero-fetoplacental circulation in pregnancy.
Not available
S-EPMC10711460 | biostudies-literature
ProteomicsZNF322A_lung cancer_iTRAQ_LC-MSMS
ZNF322A, a transcription factor, has been identified as a novel putative oncogene in lung cancer. There are over 50% of amplification rates in both Asia and Caucasian lung cancer patients. This study is to use proteomics approach to establish the protein interaction network of ZNF322A.
ORGANISM(S): Homo sapiens (Human) 
2016-07-07 | PXD001123 | Pride
Znf322a Lung cancer Itraq 
UnknownProteomic analysis of human placental syncytiotrophoblast microvesicles in preeclampsia.
Not available
S-EPMC4247627 | biostudies-literature
Sort   by:  
 Page size