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ProteomicsQuantitative phosphoproteomics analysis uncovers the regulatory networks of ZNF322A in lung cancer cells
Cys2His2 (C2H2)-type zinc finger (ZNF) is one of the most common DNA-binding motif and plays a major role as transcription factors, which encoded by 2% of human genes. C2H2 type ZNFs are reported as proteins of great versatility, such as regulation of differentiation, development, metabolism, cell s...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD015936 | Pride
Znf322a Phosphoproteomics Human lung cancer 
ProteomicsZNF322A_lung cancer_iTRAQ_LC-MSMS
ZNF322A, a transcription factor, has been identified as a novel putative oncogene in lung cancer. There are over 50% of amplification rates in both Asia and Caucasian lung cancer patients. This study is to use proteomics approach to establish the protein interaction network of ZNF322A.
ORGANISM(S): Homo sapiens (Human) 
2016-07-07 | PXD001123 | Pride
Znf322a Lung cancer Itraq 
UnknownDysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression.
Not available
S-EPMC7481419 | biostudies-literature
TranscriptomicsOncogenic zinc finger protein ZNF322A promotes lung cancer stemness through transcriptionally suppressing c-Myc expression [RNA-Seq]
ZNF322A, a C2H2 zinc finger transcription factor, is an oncoprotein in lung cancer. However, the transcription mechanisms of ZNF322A in lung cancer stemness remain elusive. By integrating our chromatin immunoprecipitation-sequencing and RNA-sequencing datasets, we identified and validated transcript...
ORGANISM(S): Homo sapiens 
2019-09-25 | GSE94537 | GEO
GenomicsOncogenic zinc finger protein ZNF322A promotes lung cancer stemness through transcriptionally suppressing c-Myc expression [ChIP-Seq]
ZNF322A, a C2H2 zinc finger transcription factor, is an oncoprotein in lung cancer. However, the transcription mechanisms of ZNF322A in lung cancer stemness remain elusive. By integrating our chromatin immunoprecipitation-sequencing and RNA-sequencing datasets, we identified and validated transcript...
ORGANISM(S): Homo sapiens 
2019-09-25 | GSE94656 | GEO
UnknownOncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
Not available
S-EPMC4865475 | biostudies-literature
UnknownOncogenic zinc finger protein ZNF322A promotes stem cell-like properties in lung cancer through transcriptional suppression of c-Myc expression.
Not available
S-EPMC6748145 | biostudies-literature
UnknownZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer.
Not available
S-EPMC7310457 | biostudies-literature
GenomicsHomo sapiens
Oncogenic zinc finger protein ZNF322A promotes lung cancer stemness through transcriptionally suppressing c-Myc expression [ChIP-Seq]
PRJNA373804 | ENA
GenomicsHomo sapiens
Oncogenic zinc finger protein ZNF322A promotes lung cancer stemness through transcriptionally suppressing c-Myc expression [RNA-Seq]
PRJNA371739 | ENA
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