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UnknownSingle-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
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S-EPMC5748184 | biostudies-literature
TranscriptomicsSingle-nucleus RNA-seq of FACS-enriched Glp1r-Sun1-sfGFP nuclei from mouse hypothalamus, dorsal vagal complex, and nodose ganglion
Glucagon-like peptide-1 receptor (GLP1R) agonists such as semaglutide reduce food intake and body weight, and Glp1r-expressing neurons in the hypothalamus and hindbrain mediate these effects. To profile these cells directly, Glp1r-Cre mice were crossed to the Gt(ROSA)26Sor-CAG-Sun1-sfGFP reporter, w...
ORGANISM(S): Mus musculus 
2026-09-14 | E-MTAB-17566 | biostudies-arrayexpress
TranscriptomicsLotus Flower-Bud Transcriptome or Gene expression
Flower-lotus with many attractive floral characteristics has been studied and discussed the most. These characteristics are used as the standards of the classification in most cases, and always attracted the attention of lotus breeders on improvement program because of associating with ornamental an...
ORGANISM(S): Nelumbo nucifera 
2014-12-08 | E-GEOD-57601 | biostudies-arrayexpress
ProteomicsNaringenin targets PI3K p85alpha to suppress PI3K/AKT signaling pathway and ameliorate disordered MMP-9 secretion in cigarette smoke extract-induced alveolar macrophages in vitro
Naringenin has demonstrated potential therapeutic effects against cigarette smoke-induced lung injury; however, its underlying mechanisms of regulating matrix metalloproteinase-9 (MMP-9) in alveolar macrophages remain unclear. Methods: The regulatory mechanisms of naringenin in cigarette smoke extra...
ORGANISM(S): Mus Musculus 
2025-04-21 | PXD063137 |
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