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ProteomicsProfiling of Subclass-Specific IgG Glycosylation in Colorectal Cancer
Changes in IgG glycosylation have been reported to be associated with colorectal cancer (CRC), but the alteration in specific subclass of IgG is unknown. Herein, we optimized five common IgG glycopeptides enrichment methods to acquire comprehensive profiling of IgG glycoproteomics in CRC. Notably, i...
ORGANISM(S): Homo sapiens (Human) 
2022-10-27 | PXD016318 | Pride
Human Serum igg Complete tryptic digestion Colorectal Lc-ms/ms 
ProteomicsComprehensive proteomic characterization reveals subclass-specific molecular aberrations within triple-negative breast cancer
Triple-negative breast cancer (TNBC) is regarded as the most aggressive subtype of breast cancer lacking targeted therapies. This is attributed to its high heterogeneity that complicates elucidation of its molecular aberrations. Here, we report identification of specific proteome expression profiles...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD017025 | Pride
Triple-negative Tnbc Proteomics Mass spectrometry Protease Breast cancer Kinase 
TranscriptomicsTMPRSS2-ERG fusion prostate cancer is a molecularly distinct estrogen-sensitive subclass of aggressive prostate cancer
Common epithelial cancers are believed to become more aggressive through the accumulation of multiple independent molecular events that lead to the deregulation of cell signaling. However, the discovery that the majority of prostate cancers harbor gene fusions of the 5'-untranslated region of androg...
ORGANISM(S): Homo sapiens 
2008-05-27 | E-GEOD-8402 | biostudies-arrayexpress
ProteomicsProfiling of Subclass-Specific IgG Glycosylation in Gastric Cancer by nanoLC-ESI-MS/MS
Background:Gastric cancer (GC) is one of the most aggressive gastrointestinal malignancy and leading cause of cancer related deaths worldwide,warranting the urgent discovery of biomarkers for early detection. IgG glycosylation is strongly related to disease progression and specific IgG glycans have ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD027475 | Pride
Human Gastric cancer Serum igg Subclass specific Lc-ms 
TranscriptomicsTranscription profiling of human colorectal serrated adenocarcinomas and conventional adenocarcinomas reveals they are a molecular subclass as well as morphologically distinct
Serrated adenocarcinomas are morphologically different from conventional adenocarcinomas. The serrated pathway has recently been proposed to represent a novel mechanism of colorectal cancer (CRC) formation. However, whether they are biologically different and truly form a distinct subclass of CRC, i...
ORGANISM(S): Homo sapiens 
2007-10-27 | E-GEOD-4045 | biostudies-arrayexpress
UnknownRelative Quantitation of Subclass-Specific Murine IgG Fc N-Glycoforms by Multiple Reaction Monitoring.
Not available
S-EPMC7178347 | biostudies-literature
GenomicsFunctional enhancer elements drive subclass-selective expression from mouse to primate neocortex
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex
PRJNA988149 | ENA
UnknownIn-depth analysis of subclass-specific conformational preferences of IgG antibodies.
Not available
S-EPMC4285876 | biostudies-literature
UnknownComprehensive Proteomic Characterization Reveals Subclass-Specific Molecular Aberrations within Triple-negative Breast Cancer.
Not available
S-EPMC7015993 | biostudies-literature
UnknownEnhancer viruses for combinatorial cell-subclass-specific labeling.
Not available
S-EPMC8610077 | biostudies-literature
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