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ModelsSubramanian2017 - Metabolic adaptations of Leishmania parasite, Genome-scale constraint-based model of Leishmania infantum
The uploaded model is linked to the Scientific Reports article: Subramanian, A., Sarkar, R.R. Revealing the mystery of metabolic adaptations using a genome scale model of Leishmania infantum . Sci Rep 7, 10262 (2017). https://doi.org/10.1038/s41598-017-10743-x. Human macrophage phagolysosome and san...
2020-10-13 | MODEL2010130001 | BioModels
ModelsSubrmanian2015 - Energy metabolism of Leishmania infantum, constrain-based metabolic model
The uploaded model is linked to the PLoS ONE article: Subramanian A, Jhawar J, Sarkar RR (2015) Dissecting Leishmania infantum Energy Metabolism - A Systems Perspective. PLoS ONE 10(9): e0137976. https://doi.org/10.1371/journal.pone.0137976. The reconstructed network consists of 142 genes encoding f...
2020-10-13 | MODEL2010130002 | BioModels
TranscriptomicsInvestigation of Gene Expression Changes in Human Umbilical Vein Endothelial cells (HUVECs) following SLC25A13 Knockdown via shRNA Lentiviral Transduction
In this study, we discover an essential role for the mitochondrial glutamate-aspartate antiporter SLC25A13 in biomass synthesis in endothelial cells (ECs). To delineate the global changes of SLC25A13 silencing at a molecular level, we performed high-throughput bulk RNA-sequencing and analyzed the di...
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-14591 | biostudies-arrayexpress
MetabolomicsEndothelial SLC25A13 links glutamine metabolism to angiogenesis
Attention to exploring endothelial cell (EC) metabolism is increasing, but a holistic perspective on the metabolic adaptations of ECs during angiogenic proliferation, is still missing. Here, we use a previously in-house developed computational EC-adapted genome scale metabolic model that recapitulat...
2026-08-10 | MTBLS15306 | MetaboLights
UnknownENDOTHELIAL SLC25A13 LINKS GLUTAMINE METABOLISM TO ANGIOGENESIS
Not available
S-SCDT-10_1038-S44321-026-00524-3 | biostudies-other
TranscriptomicsMAPC culture condition supports the derivation of cells with nascent hypoblast features from bone marrow and blastocysts
Rat Extraembryonic Endoderm Precursor (XEN-P) cells resemble the nascent hypoblast of the blastocyst. Here we show that rat Multipotent Adult Progenitor Cell (rMAPC) lines derived from bone marrow (BM) exhibit salient nascent hypoblast characteristics. We could not identify cells with hypoblast feat...
ORGANISM(S): Rattus norvegicus 
2012-07-16 | E-GEOD-29114 | biostudies-arrayexpress
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