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TranscriptomicsTranscriptional hallmarks of heterogeneous neural stem cell niches of the subventricular zone.
Throughout postnatal life in mammals, neural stem cells (NSCs) are located in the subventricular zone (SVZ) of the lateral ventricles. The greatest diversity of neuronal and glial lineages they generate occurs during early postnatal life in a region-specific manner. In order to evaluate potential he...
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-60905 | biostudies-arrayexpress
Transcriptomicssubventricular zone progenitors healthy vs. Experimental Autoimmune Encephalomyelitis mice
Transcriptional profiling of subventricular zone (SVZ) progenitors comparing control healthy mice to mice induced to develop an autoimmune demyelination (EAE model). Goal was to unveil genes involved in demyelination-induced reactivity of SVZ progenitors. Two-condition experiment, healthy vs. EAE de...
ORGANISM(S): Mus musculus 
2013-09-09 | E-GEOD-47486 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of adult mouse subventricular zone progenitor cells during the onset of differentiation
Adult mouse subventricular zone (SVZ) neural progenitor cells (NPCs) retain the capacity to generate multiple lineages in vitro and in vivo. Thus far, the mechanisms involved in the regulation of these cells have not been well elucidated. We have carried out RNA profiling of adult SVZ cell cultures ...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-4496 | biostudies-arrayexpress
TranscriptomicsExpression data from adult rat subventricular zone cells
Transforming growth factor (TGF)-ß1 is a multifunctional cytokine regulating a number of physiological and patho-physiological processes in the adult brain. Its expression is elevated during neurodegeneration, which is associated with reduced levels of neurogenesis. We have postulated that TGF-ß1 mi...
ORGANISM(S): Rattus norvegicus 
2011-05-10 | E-GEOD-14562 | biostudies-arrayexpress
TranscriptomicsExpression data from adult rat subventricular zone cells
Transforming growth factor (TGF)-ß1 is a multifunctional cytokine regulating a number of physiological and patho-physiological processes in the adult brain. Its expression is elevated during neurodegeneration, which is associated with reduced levels of neurogenesis. We have postulated that TGF-ß1 mi...
ORGANISM(S): Rattus norvegicus 
2011-05-10 | E-GEOD-14556 | biostudies-arrayexpress
TranscriptomicsMicroarray data of the subventricular zone and hippocampal tissue from mice exposed to room air or hyperoxia during the neonatal period
This experiment aimed to investigate the differences in the transcriptional profile of the neurogenic niche regions of mouse pups that were raised in room air verses mouse pups that were exposed to hyperoxia during the neonatal period. Pups were housed in room air or hyperoxia (85% O2) from P0 to P1...
ORGANISM(S): Mus musculus 
2023-01-03 | E-MTAB-11332 | biostudies-arrayexpress
TranscriptomicsSingle cell expression profiling of murine subventricular zone in adult brain three days after focal celebral ischemia
Ischemic stroke is a serious medical condition that leads to the onset of neurological symptoms such as loss of motor and cognitive functions. Focal cerebral ischemia (FCI) occurs due to the interrupted blood supply to the site of injury, resulting in the demise of brain cells. The subventricular zo...
ORGANISM(S): Mus musculus 
2021-01-01 | E-MTAB-9935 | biostudies-arrayexpress
TranscriptomicsMultiple mechanisms mediate the taurine-induced proliferation of neural stem/progenitor cells from the subventricular zone of the adult mouse
Taurine was previously reported to increase the proliferation of neural precursor cells (NPCs) from subventricular zone of the mouse brain. The results of a study that aimed to understand the mechanisms of this effect are presented here. A gene expression profile analysis indicated that genes regula...
ORGANISM(S): Mus musculus 
2013-12-21 | E-GEOD-53547 | biostudies-arrayexpress
TranscriptomicsMicroarray of neural progenitor cells from neonatal lung injury mice treated with placebo or umbilical-cord mesenchymal stromal cell extracellular vesicles or untreated, as well as age-matched control mice
The purpose of this experiment was to determine the transcriptional differences between neural progenitor cells from neonatal lung injury mice vs. control mice, as well as neonatal lung injury mice treated with umbilical-cord mesenchymal stromal cell extracellular vesicles vs. neonatal lung injury m...
ORGANISM(S): Mus musculus 
2022-05-17 | E-MTAB-11157 | biostudies-arrayexpress
TranscriptomicsRNA-seq of adult baboon subventricular zone primary cells
Histone 3 lysine 4 trimethylation (H3K4me3) is known to be associated with transcriptionally active or poised genes and required for postnatal neurogenesis within the subventricular zone (SVZ) in the rodent model. Previous comparisons have shown significant correlation between baboon (Papio anubis) ...
ORGANISM(S): Papio anubis 
2014-07-16 | E-GEOD-58527 | biostudies-arrayexpress
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