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MetabolomicsTranscriptomic and metabolomic changes in postharvest sugarbeet roots reveal widespread metabolic changes in storage and identify genes potentially responsible for respiratory sucrose loss
Endogenous metabolism is primarily responsible for losses in sucrose content and processing quality in postharvest sugarbeet roots. The genes responsible for this metabolism and the transcriptional changes that regulate it, however, are largely unknown. To identify genes and metabolic pathways that ...
2024-05-15 | MTBLS1106 | MetaboLights
GenomicsH3K115 marks fragile nucleosomes at regulatory sites (Sucrose Gradient fractions rep1)
H3K115 marks fragile nucleosomes at regulatory sites (Sucrose Gradient fractions rep1)
PRJNA1223903 | ENA
GenomicsH3K115 marks fragile nucleosomes at regulatory sites (Sucrose Gradient fractions rep2)
H3K115 marks fragile nucleosomes at regulatory sites (Sucrose Gradient fractions rep2)
PRJNA1279003 | ENA
TranscriptomicsRemodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates (part 4)
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Ago2/microRNA machinery has been shown to participate in stre...
ORGANISM(S): Homo sapiens 
2013-07-15 | E-GEOD-44379 | biostudies-arrayexpress
TranscriptomicsPolysome profiling and ribosome footprinting of Drosophila mature oocyte and activated egg
We use mRNA-seq in combination with polysome profiling to determine translational status for all mRNAs in Drosophila mature oocytes and activated eggs. Puromycin-treated lysates are used as a negative control in polysome profiling experiments. Additionally, we use ribosome footprinting to globally m...
ORGANISM(S): Drosophila melanogaster 
2014-06-12 | E-GEOD-52799 | biostudies-arrayexpress
TranscriptomicsLocolization of circRNA with DIS3 WT or D146N mutant in sucrose density gradient centrifugation assay
To investigate the locolization between DIS3 and circRNA in fractions form sucrose density gradient centrifugation (SDGC) assay for 293T cells
ORGANISM(S): Homo sapiens 
2025-02-16 | GSE256498 | GEO
TranscriptomicsTranslational activation of developmental mRNAs during neonatal mouse testis development
The sequence of gene regulatory events that drive neonatal germ cell development in the mammalian testis is not yet clear. We assessed changes in mRNA utilization in the neonatal testis at 1 and 4 dpp, times when the testis contains quiescent gonocytes (1 dpp) and proliferating spermatogonia (4 dpp)...
ORGANISM(S): Mus musculus 
2013-07-27 | E-GEOD-49283 | biostudies-arrayexpress
TranscriptomicsSelective mRNA translation during eIF2 phosphorylation induces expression of IBTKalpha
Disruption of protein folding in the endoplasmic reticulum triggers the Unfolded Protein Response (UPR), a transcriptional and translational control network designed to restore protein homeostasis. Central to the UPR is PERK phosphorylation of the alpha subunit of eIF2 (eIF2~P), which represses glob...
ORGANISM(S): Mus musculus 
2014-06-02 | E-GEOD-54581 | biostudies-arrayexpress
TranscriptomicsTranslational regulation of Anopheles gambiae mRNAs in the midgut during Plasmodium falciparum infection
Malaria is caused by Plasmodium parasites, which are transmitted via the bites of infected Anopheline mosquitoes. Midgut invasion is a major bottleneck for Plasmodium development inside the mosquito vectors as a rapidly responding immune system recognizes ookinetes and recruits killing factors from ...
ORGANISM(S): Anopheles gambiae 
2012-09-21 | E-GEOD-38707 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse polysome vs RNP fractions from testis obtained from prepuberttal and adult animals to investigate post transcriptional control mechanisms in gametes
Gametes rely heavily on post-transcriptional control mechanisms to regulate their differentiation. In eggs, the storage and selective temporal activation of maternal mRNAs is essential for normal development. In the male, transcription ceases during spermiogenesis necessitating the post-transcriptio...
ORGANISM(S): Mus musculus 
2007-11-23 | E-GEOD-4711 | biostudies-arrayexpress
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