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TranscriptomicsConditional deletion of Bcl6 in naive B cells
Bcl6 germline deletion causes a prominent inflammatory disease, owing to over-expression of Th2 cytokines, and affects the properties of B cells prior to immunization. Therefore we established the B cell-specific Bcl6 deletion mice and analyze the gene expression of naive B cells under physiological...
ORGANISM(S): Mus musculus 
2012-09-21 | E-GEOD-28737 | biostudies-arrayexpress
TranscriptomicsGene expressions of memory B cells and other type of B cells
To obtain insight into the genetic basis of the increase of functional activity of memory B cells over time, we compared the gene expression profiles of day 7 and day 40 NP-specific/IgG1 memory B cells, GC B cells and plasma cells in immunized WT mice and naïve B cells, before and after activation i...
ORGANISM(S): Mus musculus 
2012-09-21 | E-GEOD-11961 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lung to study the effect of prostaglandin E receptor subtype EP3 on mouse asthma model.
We examined the effect of PGE receptor EP3 subtype on mouse OVA-induced asthma model. We treat EP3 agonist 3h after OVA challenge. After 24 h of 3rd OVA challenge, whole lung was isolated and the gene expression change was determined.
ORGANISM(S): Mus musculus 
2007-09-25 | E-GEOD-2276 | biostudies-arrayexpress
TranscriptomicsSema4A, a novel serum marker of multiple sclerosis, implicates Th17 pathology and efficacy of interferon-β.
Background: Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central nervous system and the leading cause of lasting neurological disabilities in young adults. Increasing evidence suggests that early treatment prevents the development of disability. However, there have been no re...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-26484 | biostudies-arrayexpress
ProteomicsPhosphoproteome data of WT and ob/ob mice liver during starvation
Ten-week-old male mice (WT and ob/ob) were starved for 0, 2, 4, 6, 8, 12, 16, and 24 hours and liver samples were collected. Total proteins extracted during sample preparation of metabolomic analysis were subjected to the following phosphoproteomic analysis. As described above, 2 mg of protein solut...
ORGANISM(S): Mus Musculus (mouse) 
2025-05-20 | PXD053026 | JPOST Repository
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