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TranscriptomicsHuman bone marrow-derived mononuclear cells (BMMC): rheumatoid arthritis vs. osteoarthritis
Gene expression profiling of BMMC from patients with rheumatoid arthritis (RA) vs. osteoarthritis (OA). Bone marrow was obtained from patients with RA (n=9) or OA (n=10). The bone marrow samples from the 10 OA patients are used as controls.
ORGANISM(S): Homo sapiens 
2011-05-31 | E-GEOD-27390 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of histone modifications in human endometrial stromal cells [RNA-Seq]
Dramatic changes of gene expressions are known to occur in human endometrial stromal cells (ESC) during decidualization. The changes in gene expression are associated with changes of chromatin structure, which are regulated by epigenetic mechanisms such as histone modifications. Here, we investiga...
ORGANISM(S): Homo sapiens 
2015-03-03 | E-GEOD-57009 | biostudies-arrayexpress
GenomicsGenome-wide analysis of histone modifications in human endometrial stromal cells [ChIP-Seq]
Dramatic changes of gene expressions are known to occur in human endometrial stromal cells (ESC) during decidualization. The changes in gene expression are associated with changes of chromatin structure, which are regulated by epigenetic mechanisms such as histone modifications. Here, we investiga...
ORGANISM(S): Homo sapiens 
2015-03-03 | E-GEOD-57007 | biostudies-arrayexpress
TranscriptomicsInteractions of cytokines in peripheral blood cells from Systemic Lupus Erythematosus
SLE patients are always with various disease manifestation. Various cytokines are pointed interacting and playing pathological roles in SLE although the etiopathology is still obscure. In this study, we aimed to investigate the effects of cytokine interactions in the immune response of SLE patients....
ORGANISM(S): Homo sapiens 
2009-05-31 | E-GEOD-12374 | biostudies-arrayexpress
TranscriptomicsHuman peripheral blood cells: systemic lupus erythematosus vs healthy individual.
Gene expression profiling of peripheral blood cells from patients with systemic lupus erythematosus (SLE) vs healthy individual (HI). Peripheral blood was obtained from patients with SLE (n=21) and HI (n=45). Blood samples from 45 HI are used as control.
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-20864 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation profiling in cultured eutopic and ectopic endometrial stromal cells (methylation)
Profiles of genome-wide DNA methylation were investigated in isolated endometrial stromal cells from eutopic and ectopic endometrium. DNA methylation profiles were quite different between eutopic ESC and ectopic ESC, whereas no clear dfference were recognized between eutpic ESC with and without endo...
ORGANISM(S): Homo sapiens 
2013-09-07 | E-GEOD-47359 | biostudies-arrayexpress
TranscriptomicsEpigenome analysis of uterin leiomyoma and myometrium with or without leiomyoma [Methylation data]
Profiles of genome-wide DNA methylation were investigated in leiomyomas and in myometrium with and without leiomyomas. Profiles of DNA methylation in the myometrium with and without leiomyomas were quite similar while those in leiomyomas were distinct. Bisulphite converted DNA from the three uterin...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-45187 | biostudies-arrayexpress
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