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ProteomicsThe phosphoproteome of recombinant 2G12 and 353/11 mAb producing CHO-K1 cell lines
In this study, we conducted a phosphoproteomic analysis of two cell lines with differing monoclonal antibody (mAb) production levels using label-free quantification mass spectrometry (LFQ-MS). The high-producing cell line, 353/11, was compared to the lower-producing 2G12 cell line. Phosphoproteomic ...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2025-05-07 | PXD055200 | Pride
Tunicamycin Chinese hamster ovary Phosphoproteome Mass spectrometry Lfq 
ProteomicsQuantitative Proteomics Reveals Cellular Responses to Stress and Tunicamycin in CHO Cells
We conducted proteomics analysis aimed at evaluating the differences between CHO cell lines expressing 2G12 and 353/11, cells were cultured using a semi-perfusion batch process in parallel. The cells were collected and pelleted on day six, four hours after medium exchange, when both cell lines had r...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2024-07-03 | PXD049297 | Pride
Ms/ms Cho Lfq Orbitrap q exactive Proteomics 
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