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TranscriptomicsMapping and dynamics of regulatory DNA and transcription factor networks in A. thaliana
We mapped DNaseI hypersensitive sites (DHSs) and applied genomic footprinting to define in vivo transcription factor (TF) occupancy at nucleotide resolution across the A. thaliana genome in whole seedlings during heat- and light-response states. We find that trait-associated variation localizes with...
ORGANISM(S): Arabidopsis thaliana 
2013-12-15 | E-GEOD-53322 | biostudies-arrayexpress
UnknownImmune-mediated diarrhea and colitis with normal biochemical, endoscopic and histologic findings: a retrospective study.
Not available
S-EPMC12850695 | biostudies-literature
UnknownMethods to predict the timing and status of biological maturation in male adolescent soccer players: A narrative systematic review.
Not available
S-EPMC10490883 | biostudies-literature
ProteomicsDevelopment of a novel minimally invasive sampling and analysis technique for bioarchaeological proteomics
Here we present the development of a novel minimally invasive sample preparation technique for application in the mass spectrometric analysis of bioarchaeological materials. The extraction protocol was developed by applying commercially available, dermatology grade skin sampling strips to modern ski...
ORGANISM(S): Homo sapiens (Human) 
2022-04-06 | PXD029003 | Pride
Bioarchaeology  human  proteomics  minimally invasive sampling  mass spectrometry  lc-msms 
TranscriptomicsTriplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation [RNA-Seq]
Down syndrome (DS) confers a 20-fold increased risk of B cell acute lymphoblastic leukemia (ALL), yet the mechanisms underlying this association are undefined.  We show that triplication of only 31 genes orthologous to the putative DS Critical Region (DSCR) on chr.21q22 is sufficient to promote B ce...
ORGANISM(S): Mus musculus 
2014-04-20 | E-GEOD-48553 | biostudies-arrayexpress
GenomicsTriplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation [ChIP-seq]
Children with Down syndrome (DS) have a 20-fold increased risk of developing B cell acute lymphoblastic leukemia (B-ALL). Polysomy 21 (i.e., extra copies of chr.21) is also the most frequent somatic aneuploidy among all B-ALLs. Additional B-ALLs harbor intrachromosomal amplifications of chr.21q22 (i...
ORGANISM(S): Mus musculus 
2014-04-20 | E-GEOD-48534 | biostudies-arrayexpress
Unknown11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis.
Not available
S-EPMC3606528 | biostudies-literature
UnknownFibroblast growth factor-21 is required for weight loss induced by the glucagon-like peptide-1 receptor agonist liraglutide in male mice fed high carbohydrate diets.
Not available
S-EPMC10131131 | biostudies-literature
UnknownRisk factors for suicidality in Huntington disease: An analysis of the 2CARE clinical trial.
Not available
S-EPMC6448454 | biostudies-literature
UnknownBRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance.
Not available
S-EPMC11299415 | biostudies-literature
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