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The budding yeast E3 SUMO ligase Mms21, a component of the Smc5-6 complex, regulates sister chromatid cohesion, DNA replication, and DNA repair. We identify a role for Mms21 in ribosome biogenesis. The mms21RINGD mutant exhibits reduced rRNA production, nuclear accumulation of 60S and 40S ribosomal ...
ORGANISM(S): Saccharomyces cerevisiae 
SUMO E3 ligase SIZ1 sustains nuclear condensate-mediated immune activation in plants
mRNA profiling of WI38 wild-type or overexpressiong the SUMO E3 ligase PIASy in human primary fibroblasts 24h post-infection. The goal of this study is to analyse transcriptional changes in cells over-expressing the SUMO E3 ligase PIASy and to compare them with ChIPseq data for several histones mark...
ORGANISM(S): Homo sapiens 
Proteomic Analysis of the total proteome from Arabidopsis thaliana SUMO E3 Ligase mutants siz1-2 and mms21-1 and wild-type (Col-0) 8-day old seedlings
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-04-23 | PXD009274 | Pride
SUMO E3 Ligase SIZ1-mediated SUMOylation of LBD29 positively regulates lateral root formation in Arabidopsis thaliana
The budding yeast E3 SUMO ligase Mms21, a component of the Smc5-6 complex, regulates sister chromatid cohesion, DNA replication, and DNA repair. We identify a role for Mms21 in ribosome biogenesis. The mms21RINGD mutant exhibits reduced rRNA production, nuclear accumulation of 60S and 40S ribosomal ...
ORGANISM(S): Saccharomyces cerevisiae 
2015-06-13 | GSE69826 | GEO
Protein inhibitor of activated STAT (PIAS) are E3 SUMO ligases playing important roles in protein stability and signaling transduction pathways. PIAS proteins are overexpressed in the triple-negative breast cancer cell line MDA-MB-231, and PIAS knockout (KO) results in a reduction in cell proliferat...
ORGANISM(S): Homo sapiens (Human) 
2023-02-02 | PXD023841 | Pride
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