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MetabolomicsBranched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming

Macrophages are prominent immune cells in the tumor microenvironment that can be educated into pro-tumoral phenotype by tumor cells to favor tumor growth and metastasis. The mechanisms that mediate a mutualistic relationship between tumor cells and macrophages remain poorly characterized. Here, w...

2022-10-03 | MTBLS4497 | MetaboLights
ProteomicsA Bifunctional SPD-0090 contributes virulence of Streptococcus pneumoniae by affecting iron transport and galactose metabolism
Streptococcus pneumoniae (S.pneumoniae) is a Gram-positive bacterial pathogen that colonizes on the mucosal surfaces of the host's nasopharynx and upper respiratory tract and results in pneumonia. In order to survive and infect the host, S.pneumoniae must have obtain essential nutrients, such as tra...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2022-06-01 | PXD030183 | Pride
Spd-0090 Virulence Iron transport protein Galactose metabolism Streptococcus pneumoniae 
UnknownDevelopment and validation of a clinico-biological score for Brucella spondylitis: a two-center study.
Not available
S-EPMC12573889 | biostudies-literature
UnknownXimaoornatins A-C, Polyoxygenated Diterpenoids from the Hainan Soft Coral Sinularia ornata.
Not available
S-EPMC8950289 | biostudies-literature
UnknownSynthesis and evaluation of a new bifunctional NETA chelate for molecular targeted radiotherapy using(90)Y or(177)Lu.
Not available
S-EPMC4670554 | biostudies-literature
UnknownShort-Term Responses of Soil Respiration and C-Cycle Enzyme Activities to Additions of Biochar and Urea in a Calcareous Soil.
Not available
S-EPMC5010292 | biostudies-literature
UnknownUpper Respiratory Tract Viral Ribonucleic Acid Load at Hospital Admission Is Associated With Coronavirus Disease 2019 Disease Severity.
Not available
S-EPMC7454839 | biostudies-literature
UnknownReward network mechanism in anhedonia and depression.
Not available
S-EPMC12445566 | biostudies-literature
TranscriptomicsEffects of miR-126/126* of cytokine/chemokine expression in tumor-derived 4T1 cells
In order to test the effects of metastasis suppressive miR-126/126* on primary tumor microenvironment, we designed a real-time PCR-based mouse cytokine/chemokine array containing 95 cytokines/chemokines and their receptors. Considering the possibility that production of cytokines/chemokines may be d...
ORGANISM(S): Mus musculus 
2012-12-13 | E-GEOD-42885 | biostudies-arrayexpress
UnknownNaturally Occurring Resistance-Associated Variants to Hepatitis C Virus Direct-Acting Antiviral Agents in Treatment-Naive HCV Genotype 6a-Infected Patients.
Not available
S-EPMC5661091 | biostudies-literature
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