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ProteomicsAdaptiven mechanism of antibiotic resistant Staphylococus aureus to host environment
Antibiotic-resistant bacteria can escape from the killing of host immune and settle in the host to form persistent infections. In this study, we investigated the environmental adaptation mechanism of resistant Staphyloccus aureus (S. aureus) to host environment by Data-independent acquisition based ...
ORGANISM(S): Staphylococcus aureus 
2022-05-31 | PXD029584 | Pride
Host environment Ciprofloxacin-resistant Proteomics Staphylococcus aureus 
ProteomicsNucleolar beacon for monitoring nucleolar morphology and proteomics in living cells
A novel approach combined nucleolar beacon with proximity labeling to obtain the nucleolar proteome. These techniques offer effective tools for investigating nucleolar functions in living cells and present a potential application method for drug delivery.
ORGANISM(S): Homo sapiens (Human) 
2025-06-23 | PXD059125 | Pride
Nucleolar proteomics nucleolar beacon proximity labeling 
ProteomicsProteomics coupled transcriptomics reveals lipopolysaccharide inhibiting peroxisome proliferator-activated receptors signalling pathway to reduce lipid droplets accumulation in mouse liver
Lipid droplets (LDs) are multifunctional organelles consisting of a central compartment of non-polar lipids shielded from the cytoplasm by a phospholipid monolayer. The excessive accumulation of lipid droplets in cells is closely related to the development and progression of many diseases in humans ...
ORGANISM(S): Mus Musculus 
2023-01-27 | PXD039724 |
ProteomicsNoninvasive urinary protein signatures associated with colorectal cancer diagnosis and metastasis
Colorectal cancer is the 3rd commonly diagnosed cancer (10.2%) and 2nd cause of cancer death (9.2%) in all cancers.There will be estimated 1.8 million new colorectal cancer cases and 0.9 million colorectal cancer deaths in 20181. As the 5th incidence rates and mortality rates cancer in china, colore...
ORGANISM(S): Homo Sapiens 
2022-03-15 | PXD032291 |
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