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ProteomicsRattus norvegicus lung LC-MS/MS
Male Sprague-Dawley rats were used to establish exhausted-exercise model by motorized rodent treadmill. Yu-Ping-Feng-San at doses of 2.18 g/kg was administrated by gavage before exercise training for 10 consecutive days. Quantitative proteomics was performed for assessing the related mechanism of Yu...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-08-12 | PXD032737 | Pride
Rattus norvegicus Lung tissue Lc-ms/ms 
UnknownEvaluating the effect of tanning response to sun exposure on the risk of skin diseases through Mendelian randomization.
Not available
S-EPMC9478173 | biostudies-literature
ProteomicsExosomes from mesenchymal stromal cells reduce murine colonic inflammation via a macrophage-dependent mechanism
Conventional treatments for inflammatory bowel disease (IBD) have multiple potential side effects. Therefore, alternative treatments are desperately needed. In the present study, we proposed a new therapeutic tool for the treatment of IBD in murine pre-clinical models by using MSC-Exos. We demonstra...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-05-27 | PXD015386 | Pride
Inflammatory bowel disease Exosomes Macrophages Mesenchymal stromal cells 
TranscriptomicsComparative Transcriptomics of Soybean Near Isogenic Lines in Response to Phytophthora Sojae
Phytophthora root and stem rot (PRR) of soybean, caused by Phytophthora sojae, is effectively controlled by Rps genes in soybean. Rps genes are race-specific, yet the mechanism of resistance, as well as susceptibility, remains largely unclear. Taking advantage of RNA-seq technology, we sequenced the...
ORGANISM(S): Glycine max 
2014-04-16 | E-GEOD-48524 | biostudies-arrayexpress
MetabolomicsMirabegron displays anticancer effects by globally browning adipose tissues

Metabolic reprogramming in malignant cells is a hallmark of cancer that relies on augmented glycolytic metabolism to support their growth, invasion and metastasis. However, the impact of global adipose metabolism on tumor growth and the drug development by targeting adipose metabolism remain larg...

2023-11-08 | MTBLS8682 | MetaboLights
UnknownMetabolic parameter of baseline 18 F-FDG PET/CT with PINK models improve the prediction of treatment outcome in extranodal NK/T-cell lymphoma treated with P-GEMOX chemotherapy.
Not available
S-EPMC11971060 | biostudies-literature
Proteomics,MultiomicsAPOBEC3A is an Oral Cancer Prognostic Biomarker in Taiwanese Carriers of an APOBEC Deletion Polymorphism
Chen T-W, Lee C-C, Liu H, Wu C-S, Pickering CR, Huang P-J, et al., Nature Communications 8, Article number: 465 (2017) doi:10.1038/s41467-017-00493-9

Oral squamous cell carcinoma is a prominent cancer worldwide, p...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084250 | MassIVE
UnknownSelective anti-tumor activity of glutathione-responsive abasic site trapping agent in anaplastic thyroid carcinoma
Not available
S-EPMC11229194 | biostudies-literature
UnknownPrognostic value of preoperative C-reactive protein to albumin ratio in patients with thymic epithelial tumors: a retrospective study.
Not available
S-EPMC9670652 | biostudies-literature
MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
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