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GenomicsGlobal analysis of in vivo EGR1-binding sites in erythroleukemia cell K562 using chromatin immunoprecipitation and massively parallel sequencing
Early growth response gene 1 (EGR1) has been implicated in megakaryocyte differentiation induced by PMA (phorbol 12-myristate 13-acetate). The identification of direct EGR1 target genes in global scale is critical for our understanding of how EGR1 contributes to this process. In this study, we provi...
ORGANISM(S): Homo sapiens 
2010-09-08 | E-GEOD-21665 | biostudies-arrayexpress
TranscriptomicsIntrathymic T-cell selection
Comparisons between untreated primary cells T-cell precursors from the thymus. CD69- thymocytes are from Zap70-deficent mice and are >95% CD4+CD8+. These cells fail to generate intrathymic TCR signals as a result of their lacking Zap70 molecules, and are thus representative of "preselection" CD4+CD8...
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-2262 | biostudies-arrayexpress
ProteomicsDataset for quantitative phospho-proteomics analysis of a serial hepatoma cell lines with increasing invasion and metastasis potential
Here, we used isobaric tags for relative and absolute quantitation (iTRAQ) based quantitative phospho-proteomics approach to identify biomarkers associated with hepatoma recurrence/metastasis in hepatoma cell lines with increasing metastasis ability.
ORGANISM(S): Homo Sapiens 
2019-09-25 | PXD015569 |
Proteomics4E-BP1Ser37 phosphorylation associate with poor prognosis in HCC revealed by quantitative phosphoproteomics of portal vein tumor thrombus
Hepatocellular Carcinoma(HCC)is one of the most common malignat tumor,which is causing the second leading cancer-related death worldwide.
ORGANISM(S): Homo Sapiens 
2019-09-25 | PXD015570 |
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