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TranscriptomicsSystematic characterization of seminal plasma piRNAs as molecular biomarkers for male infertility
Although piwi-interacting RNAs (piRNAs) play pivotal roles in spermatogenesis, little is known about piRNAs in the seminal plasma of infertile males. In this study, we systematically investigated the profiles of seminal plasma piRNAs in infertile males to identify piRNAs that are altered during infe...
ORGANISM(S): Homo sapiens 
2016-06-28 | E-GEOD-78131 | biostudies-arrayexpress
ProteomicsA brain signaling framework for stress-induced depression and ketamine treatment elucidated by phosphoproteomics
Depression is a common affective disorder characterized by significant and persistent low mood.Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, is reported to have a rapid and durable antidepressant effect.
ORGANISM(S): Mus Musculus 
2019-11-18 | PXD016302 |
ProteomicsTumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks Nuclear Factor-κB activation in hepatocellular carcinoma
Background: Tumor necrosis factor α-induced protein 1 (TNFAIP1) is frequently downregulated in cancer cell lines and promotes cancer cell apoptosis. However, its role, clinical significance and molecular mechanisms in hepatocellular carcinoma (HCC) are unknown. Methods: The expression of TNFAIP1 in...
ORGANISM(S): Homo Sapiens 
2019-11-19 | PXD016329 |
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