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MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Untargeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights
UnknownLOX and Its Methylation Impact Prognosis of Diseases and Correlate with TAM Infiltration in ESCA.
Not available
S-EPMC9452977 | biostudies-literature
UnknownUsing multi-focus group method as an effective tool for eliciting business system requirements: Verified by a case study.
Not available
S-EPMC10027421 | biostudies-literature
UnknownA transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker.
Not available
S-EPMC10784309 | biostudies-literature
ProteomicsHSPA1A and DNAJB1 regulate NELF condensate reversibility to safeguard transcriptional recovery under heat stress
The negative elongation factor (NELF) is essential in establishing RNA Polymerase II (Pol II) pausing at promoter-proximal regions, providing a key regulatory checkpoint for precise gene expression control. In response to heat shock (HS) stress, NELF has been observed to form nuclear condensates, bu...
ORGANISM(S): Homo Sapiens 
PXD064175 |
UnknownEvaluation of the therapeutic effects of QuickOpt optimization in Chinese patients with chronic heart failure treated by cardiac resynchronization.
Not available
S-EPMC5844885 | biostudies-literature
UnknownSimulation to become a better neurosurgeon. An international prospective controlled trial: The Passion study.
Not available
S-EPMC11134543 | biostudies-literature
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