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Reactive oxygen species have been established to play a critical role in pancreatic carcinogenesis. One of the main antioxidant enzymes is mitochondrial superoxide dismutase (Sod2). Sod2 has been shown to affect tumor initiation and metastatic progression in various cancer types. The impact of Sod2 ...
ORGANISM(S): Mus musculus 
CuZn-superoxide dismutase (CuZn-SOD) and ascorbate peroxidase (APX) constitute first line of defence against oxidative stress. In the present study, PaSOD and RaAPX genes from Potentilla atrosanguinea and Rheum australe, respectively were overexpressed individually as well as in combination in Arabi...
ORGANISM(S): Arabidopsis thaliana 
Enterocyte Superoxide Dismutase 2 Deletion Drives Hyperinsulinemia and Obesity
This transcription profiling time course experiment was conducted in order to analyze the cellular response of the plasmid-free expression system E.coli BL21(DE3)::TN7 to high level expression of recombinant human super-oxide-dismutase (SOD).Three biological replicates were generated by usi...
ORGANISM(S): Escherichia coli 
IMS-MS data for Cu/Zn-Superoxide Dismutase (from bovine erythrocytes). Experiments were conducted on two different IMS platforms (DTIMS and TIMS) to compare the CCS values obtained under different types of IMS. Three separate solution conditions were used for the DTIMS data in order to obtain CCS va...
ORGANISM(S): Bovine (from Erythrocytes) 
Elemental stoichiometry of biomass is a focal point that connects different biogeochemical cycles. Yet, the mechanistic underpinnings of elemental stoichiometry are poorly quantified in many cases. We combined targeted and untargeted metaproteomics, Bayesian statistical modelling, and geochemical me...
ORGANISM(S): environmental samples <diatoms environmental samples <haptophytes 
2026-08-13 | PXD076644 | Pride
Switch of mitochondrial superoxide dismutase into a prooxidant peroxidase in manganese-deficient cells
Mitochondrial antioxidant defence was manipulated by dexamthasone inducible RNAi knockdown of the mitochondrial superoxide dismutase (MSD1) to study transcriptional changes in response.
ORGANISM(S): Arabidopsis thaliana 
The body’s defense against schistosome infection can take many forms. For example, upon developing acute schistosomiasis, patients often have fever coinciding with larval maturation, migration and early oviposition. As the infection becomes established, the parasite comes under oxidative stress gene...
ORGANISM(S): Schistosoma mansoni 
Natural plant-derived superoxide dismutase nanoenzyme for sepsis-induced liver injury therapy.
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