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ProteomicsFunction and relevance of sushi domain-containing protein 2 (SUSD2) in circulating tumor cells of metastatic estrogen receptor positive breast cancer
Albeit responding well to therapy, estrogen receptor positive breast cancers frequently become subsequently resistant. This leads to distant metastasis and release of circulating tumor cells (CTCs) into the blood stream and ends with the death of the patient. Here we analyzed the proteome of CTC-ITB...
ORGANISM(S): Homo sapiens (Human) 
2025-02-04 | PXD047444 | Pride
Breast cancer Susd2 Estrogen receptor positive Circulating tumor cells Metastasis 
TranscriptomicsDECIDUALIZATION INDUCES A SECRETOME SWITCH IN THE PERIVASCULAR NICHE CELLS OF THE HUMAN ENDOMETRIUM
The endometrial perivascular microenvironment is rich in mesenchymal stem-like cells that express type 1 integral membrane protein Sushi domain containing 2 (SUSD2) but the role of these cells in the decidual transformation of this tissue in pregnancy is unknown. We used an antibody directed against...
ORGANISM(S): Homo sapiens 
2014-10-29 | E-GEOD-57182 | biostudies-arrayexpress
UnknownMultiple functions of sushi domain containing 2 (SUSD2) in breast tumorigenesis.
Not available
S-EPMC4426260 | biostudies-literature
UnknownSUSD2 suppresses CD8+ T cell antitumor immunity by targeting IL-2 receptor signaling.
Not available
S-EPMC9669207 | biostudies-literature
UnknownIn Vitro Implantation Model Using Human Endometrial SUSD2+ Mesenchymal Stem Cells and Myometrial Smooth Muscle Cells.
Not available
S-EPMC8181319 | biostudies-literature
UnknownSUSD2 Proteolytic Cleavage Requires the GDPH Sequence and Inter-Fragment Disulfide Bonds for Surface Presentation of Galectin-1 on Breast Cancer Cells.
Not available
S-EPMC6696261 | biostudies-literature
UnknownSUSD2 expression correlates with decreased metastasis and increased survival in a high-grade serous ovarian cancer xenograft murine model.
Not available
S-EPMC7299533 | biostudies-literature
GenomicsCBX8 together with SET facilitates ovarian carcinoma growth and metastasis by suppressing the transcription of SUSD2
CBX8 together with SET facilitates ovarian carcinoma growth and metastasis by suppressing the transcription of SUSD2
PRJNA790071 | ENA
GenomicsGene expression profile magnetic beads sorted CD8+ T cells from naïve splenocytes and OVA257-264 peptide activated splenocytes from WT and Susd2-/- OT-I mice
Gene expression profile magnetic beads sorted CD8+ T cells from naïve splenocytes and OVA257-264 peptide activated splenocytes from WT and Susd2-/- OT-I mice
PRJNA874422 | ENA
TranscriptomicsCBX8 together with SET facilitates ovarian carcinoma growth and metastasis by suppressing the transcription of SUSD2
CBX8 promotes cell proliferation and migration through downregulating the expression of SUSD2.The mRNAs from SKOV3 cells expressing control shRNAs or CBX8 shRNAs were extracted and subjected to RNA-seq.
ORGANISM(S): Homo sapiens 
2021-12-21 | GSE191191 | GEO
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