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TranscriptomicsThe Menin-Bach2 axis is critical for regulating CD4 T cell senescence and cytokine homeostasis
Although CD4 T cell senescence plays an important role in immunosenescence, the mechanism behind this process remains unclear. Here we show that T cell-specific Menin deficiency results in the premature senescence of CD4 T cells, which is accompanied by the senescence-associated secretory phenotype...
ORGANISM(S): Mus musculus 
2014-03-27 | E-GEOD-49968 | biostudies-arrayexpress
UnknownRegulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2.
Not available
S-EPMC8820811 | biostudies-literature
UnknownControl of the stochastic response of magnetization dynamics in spin-torque oscillator through radio-frequency magnetic fields.
Not available
S-EPMC8357834 | biostudies-literature
TranscriptomicsA genome-wide expression profile of steroidogenic cells selectively isolated from adrenal glands of knockout mice lacking steroidogenic acute regulatory protein
Steroidogenic acute regulatory protein (Star) facilitates cholesterol transfer into the inner mitochondrial membrane in the acute and regulated production of steroid hormones. Mice lacking Star (Star-/-) share the phenotypes with patients with congenital lipoid adrenal hyperplasia such as compromise...
ORGANISM(S): Mus musculus 
2011-08-13 | E-GEOD-31328 | biostudies-arrayexpress
TranscriptomicsRole of calcium/calmodulin-dependent kinase type IV in podocyte function in lupus nephritis
Kidney podocytes and their slit diaphragms contribute to prevent urinary protein loss. T cell from patients with systemic lupus erythematosus display increased expression of calcium/calmodulin kinase IV (CaMKIV). Here we evaluated the functional role of CaMKIV in lupus nephritis (LN) using kidney b...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-55768 | biostudies-arrayexpress
ProteomicsLFQ of GFP-Trap IP-MS of OfMasc-interacting proteins
OfMasc-GFP derivatives or GFP were transiently expressed in OfT1C/tet cells (3.2e6 cells) seeded in 10 cm-diameter culture dishes. At two days post transfection, the cells were fixed, collected, and lysed on ice for 10 min in 1 mL of RIPA buffer (20 mM HEPES-KOH, pH 7.5, 1 mM EGTA, 1 mM MgCl2, 150 m...
ORGANISM(S): Cellular Organisms 
2025-10-25 | PXD059481 | JPOST Repository
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