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ProteomicsIdentification of nascent peptides of peptidyl-tRNA dissociated from ribosome in the early elongation stage in Escherichia coli pthts cells
Accurate translation of mRNAs into functional proteins is a fundamental process in all living organisms. In bacteria, in the early stage of translation elongation, peptidyl-tRNAs (pep-tRNAs) with short nascent chains frequently dissociate from the ribosome (pep-tRNA drop-off). The dissociated pep-tR...
ORGANISM(S): Escherichia coli 
2023-05-18 | PXD030805 | Pride
Translation 
ProteomicsIdentification of nascent peptides of peptidyl-tRNA dissociated from ribosome in the early elongation stage in Escherichia coli pthts cells
Accurate translation of mRNAs into functional proteins is a fundamental process in all living organisms. In bacteria, in the early stage of translation elongation, peptidyl-tRNAs (pep-tRNAs) with short nascent chains frequently dissociate from the ribosome (pep-tRNA drop-off). The dissociated pep-tR...
ORGANISM(S): Escherichia coli 
2023-05-18 | PXD030807 | Pride
Translation 
ProteomicsIdentification of nascent peptides of peptidyl-tRNA dissociated from ribosome in the early elongation stage in Escherichia coli pthts cells
Accurate translation of mRNAs into functional proteins is a fundamental process in all living organisms. In bacteria, in the early stage of translation elongation, peptidyl-tRNAs (pep-tRNAs) with short nascent chains frequently dissociate from the ribosome (pep-tRNA drop-off). The dissociated pep-tR...
ORGANISM(S): Escherichia coli 
2023-05-18 | PXD030806 | Pride
Translation 
ProteomicsIdentification of nascent peptides of peptidyl-tRNA dissociated from ribosome in the early elongation stage in Escherichia coli pthts cells
Accurate translation of mRNAs into functional proteins is a fundamental process in all living organisms. In bacteria, in the early stage of translation elongation, peptidyl-tRNAs (pep-tRNAs) with short nascent chains frequently dissociate from the ribosome (pep-tRNA drop-off). The dissociated pep-tR...
ORGANISM(S): Escherichia coli 
2023-05-18 | PXD030808 | Pride
Translation 
TranscriptomicsPARN mediates 3'-end trimming of Argonaute-cleaved precursor microRNAs
microRNAs (miRNAs) are typically generated as ~22-nucleotide double-stranded RNAs via processing of precursor hairpins by the RNase III enzyme Dicer, after which they are loaded into Argonaute (Ago) proteins to form RNA-induced silencing complex (RISC). However, the biogenesis of miR-451, an erythro...
ORGANISM(S): Danio rerio 
2013-11-13 | E-GEOD-51036 | biostudies-arrayexpress
TranscriptomicsIdentification of baseline gene expression signatures predicting therapeutic responses to three biologic agents in rheumatoid arthritis: a retrospective observational study
The aim of this study was to identify the specific molecular biological features predicting the therapeutic outcomes of three bDMARDs, infliximab (IFX), tocilizumab (TCZ), and abatacept (ABT) by studying blood gene expression signature of patients prior to biologic treatment in a unified test platfo...
ORGANISM(S): Homo sapiens 
2016-07-21 | E-GEOD-78068 | biostudies-arrayexpress
TranscriptomicsStudy of microRNA associated with metforminM-bM-^@M-^Ys anti-tumor effect
The miRNAs expression was markedly altered with the treatment of metformin in vitro and in vivo and various miRNAs induced by metformin also may contribute to tumor growth in vitro and in vivo. Using a custom microarray platform, we analyzed the expression levels of 985 human miRNA probes in the cel...
ORGANISM(S): Homo sapiens 
2012-04-04 | E-GEOD-30289 | biostudies-arrayexpress
ProteomicsE. coli wt/delta L31, IDA, rep2
E. coli wt/delta L31 IDA acquisition for constructing SWATH library, replicate 2
ORGANISM(S): Escherichia Coli 
2017-11-05 | PXD007805 | JPOST Repository
ProteomicsE. coli wt/delta L31, SWATH, rep3
E. coli wt/delta L31 differential analysis by SWATH acquisition, library is constructed by in-house IDA acquisition, replicate 3
ORGANISM(S): Escherichia Coli 
2017-11-05 | PXD007808 | JPOST Repository
ProteomicsE. coli wt/delta L31, IDA, rep1
E. coli wt/delta L31 IDA acquisition for constructing SWATH library, replicate 1
ORGANISM(S): Escherichia Coli 
2017-11-05 | PXD007803 | JPOST Repository
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