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UnknownctDNA: An emerging neoadjuvant biomarker in resectable solid tumors.
Not available
S-EPMC8509880 | biostudies-literature
TranscriptomicsMulti-region copy-number analysis
Intra-tumour heterogeneity (ITH) foster tumour adaptation and hamper the efficiency of personalised medicine approaches. We investigated the extent of ITH within individual clear cell renal cell carcinomas (ccRCC) by multi-region sampling and copy number analysis. We analyzed 63 tumour regions and 8...
ORGANISM(S): Homo sapiens 
2013-06-04 | E-GEOD-47077 | biostudies-arrayexpress
GenomicsTRACERx esophageal adenocarcinoma
Data Access Committee EGAC00001000340
EGAC00001000340 | EGA
GenomicsTRACERx Pilot Study Data Access Committee
Data Access Committee EGAC00001000198
EGAC00001000198 | EGA
TranscriptomicsExpression data from different samples of a single ccRCC patient.
We have sampled several tumour regions from a single patient before and after everolimus treatment, including both primary and metastatic site samples to investigate intra-tumour heterogeneity. We selected 4 primary tumour regions, including a pre-treatment biopsy, and 1 metastatic region for expres...
ORGANISM(S): Homo sapiens 
2011-08-05 | E-GEOD-31232 | biostudies-arrayexpress
GenomicsTracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy
Esophageal adenocarcinomas (EACs) are associated with dismal prognosis. Deciphering the evolutionary histories of this disease may shed light on therapeutically tractable targets and reveal changing mutational processes during the disease course and following neoadjuvant chemotherapy (NAC). We exome...
EGAS00001001254 | EGA
Genomicsena-DATASET-CRUK-LRI-04-02-2014-11:46:00:265-3 - samples
Paired end Illumina sequencing of whole exomes of multiple tumour regions.
EGAD00001000734 | EGA
GenomicsGenomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
We applied multi-region exome sequencing to 10 clear cell renal carcinomas to resolve the genetic architecture, intra tumour heterogeneity and evolutionary histories of these tumours.
EGAS00001000667 | EGA
GenomicsTRACERx renal DAC
Data Access Committee EGAC00001001907
EGAC00001001907 | EGA
TranscriptomicsTranscription profiling of human patients recruited to the paclitaxel arm of the CTCR-OV01 study, pre-treatment individuals with ovarian cancer
All patients with suspected ovarian cancer (Raised CA 125 and a complex pelvic mass in a perimenopausal woman) were radiologically staged using CT scan and a chest x-ray. Patients with evidence of intra-abdominal metastasis and/or malignant pleural effusion were approached for entry to the study. Ti...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9455 | biostudies-arrayexpress
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