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ProteomicsYeast SWI/SNF complex - Loss of Snf5 Induces Formation of an Aberrant SWI/SNF Complex
This project uses crosslinked based mass spectrometry (CXMS) to study the architecture of yeast SWI/SNF complex.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-06-14 | PXD005948 | Pride
Swi/snf bs3 crosslinking architecture 
GenomicsGenome-wide profile of the SWI/SNF chromatin remodeling complex
A systems understanding of nuclear organization and events is critical for determining how cells divide, differentiate and respond to stimuli and for identifying the causes of diseases. Chromatin remodeling complexes such as SWI/SNF have been implicated in a wide variety of cellular processes includ...
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-24397 | biostudies-arrayexpress
TranscriptomicsA SWI/SNF nucleosome remodeling complex acts in non-coding RNA-mediated transcriptional silencing
RNA-mediated transcriptional silencing prevents deleterious effects of transposon activity and controls the expression of protein-coding genes. It involves long non-coding RNAs (lncRNAs)1, which in Arabidopsis thaliana are produced by a specialized RNA Polymerase V (Pol V)2. lncRNAs guide Argonaute-...
ORGANISM(S): Arabidopsis thaliana 
2012-12-01 | E-GEOD-38400 | biostudies-arrayexpress
TranscriptomicsThe Swi/Snf tumor suppressor complex establishes nucleosome occupancy at target promoters [expression]
Precise nucleosome-positioning patterns at promoters are thought to be crucial for faithful transcriptional regulation. However, the mechanisms by which these patterns are established and dynamically maintained and subsequently contribute to transcriptional control are poorly understood. The Swi/Snf...
ORGANISM(S): Mus musculus 
2013-06-04 | E-GEOD-46645 | biostudies-arrayexpress
GenomicsThe Swi/Snf tumor suppressor complex establishes nucleosome occupancy at target promoters [ChIP-seq]
Precise nucleosome-positioning patterns at promoters are thought to be crucial for faithful transcriptional regulation. However, the mechanisms by which these patterns are established and dynamically maintained and subsequently contribute to transcriptional control are poorly understood. The Swi/Snf...
ORGANISM(S): Mus musculus 
2013-06-04 | E-GEOD-46587 | biostudies-arrayexpress
GenomicsThe Swi/Snf tumor suppressor complex establishes nucleosome occupancy at target promoters [Mnase-Seq II]
Precise nucleosome-positioning patterns at promoters are thought to be crucial for faithful transcriptional regulation. However, the mechanisms by which these patterns are established and dynamically maintained and subsequently contribute to transcriptional control are poorly understood. The Swi/Snf...
ORGANISM(S): Mus musculus 
2013-06-04 | E-GEOD-46586 | biostudies-arrayexpress
GenomicsThe Swi/Snf tumor suppressor complex establishes nucleosome occupancy at target promoters [Mnase-Seq I]
Precise nucleosome-positioning patterns at promoters are thought to be crucial for faithful transcriptional regulation. However, the mechanisms by which these patterns are established and dynamically maintained and subsequently contribute to transcriptional control are poorly understood. The Swi/Snf...
ORGANISM(S): Mus musculus 
2013-06-04 | E-GEOD-38670 | biostudies-arrayexpress
ProteomicsSMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity
Chromatin remodeling complexes, such as the SWItch/Sucrose Non-Fermentable (SWI/SNF) complex, play key roles in regulating gene expression by modulating nucleosome positioning. The core subunit SMARCB1 is essential for these functions, as it anchors the complex to the nucleosome acidic patch, enabli...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD062226 | Pride
Swi/snf Smarcb1 Chromatin Complex stability Cancer 
TranscriptomicsTarget genes of BRG1 in human embryonic stem cells
BRG1-SWI/SNF complex is an important chromatin remodeling complex that involved in various biological processes. Here we described the genome-wide binding of histone acetylation upon BRG1 depletion in human embryonic stem cells. Human embryonic stem cells were treated with either scrambled siRNA or ...
ORGANISM(S): Homo sapiens 
2015-04-28 | E-GEOD-57473 | biostudies-arrayexpress
TranscriptomicsTarget genes of BRG1 in mouse embryonic stem cells
BRG1-SWI/SNF complex is an important chromatin remodeling complex that involved in various biological processes. Here we described the genome-wide binding of histone acetylation upon BRG1 depletion in mouse embryonic stem cells. Mouse embryonic stem cells were treated with either scrambled siRNA or ...
ORGANISM(S): Mus musculus 
2015-04-28 | E-GEOD-57472 | biostudies-arrayexpress
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