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TranscriptomicsRNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe [Illumina Genome Analyzer]
RNA interference (RNAi) is a gene silencing mechanism conserved from fungi to mammals. Small interfering RNAs are products and mediators of the RNAi pathway and act as specificity factors in recruiting effector complexes. The Schizosaccharomyces pombe genome encodes one of each of the core RNAi prot...
ORGANISM(S): Schizosaccharomyces pombe 972h- 
2014-01-23 | E-GEOD-54194 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport.
Cilia are ubiquitous cell surface projections that modulate various sensory- and motility based processes and are implicated in a growing number of multi-organ genetic disorders termed ciliopathies. As new components required for cilium biogenesis and function remain unidentified, we sought to furth...
ORGANISM(S): Caenorhabditis elegans 
2011-07-25 | E-GEOD-25633 | biostudies-arrayexpress
TranscriptomicsExpression data from melanoma subpopulations
We aimed at identifying lymphangiogenic subpopulations by comparative analysis of single cell clones derived from a melanoma of a single patient. Selected clones were grafted into SCID mice, where they induced lymphangiogenesis and metastasized into sentinel nodes, whereas non-lymphangiogenic clones...
ORGANISM(S): Homo sapiens 
2012-06-17 | E-GEOD-36035 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for a melanoma lesion and a cellline derived thereof
Here we report on a bulk culture termed MCM1, which was derived from a 61 year old male diagnosed with a nodular melanoma stage T2a, N0. At passage three of culturing, DNA was isolated and Affymetrix SNP6.0 array hybridizations were performed. Cultured MCM1 cells revealed overall identical copy numb...
ORGANISM(S): Homo sapiens 
2012-06-17 | E-GEOD-35991 | biostudies-arrayexpress
TranscriptomicsTime-course transcriptome analysis of a human neuronal cell line
RNA-seq analysis on a human neuronal cell line derived from fetal mesencephalon (LUHMES) from day 0 to day 6.
ORGANISM(S): Homo sapiens 
2021-07-31 | E-MTAB-8908 | biostudies-arrayexpress
TranscriptomicsTime-course transcriptome analysis of a human neuronal cell line with RFX2 KO
RNA-seq analysis on a human neuronal cell line derived from fetal mesencephalon (LUHMES) wild type and RFX2 knockout from day 0 to day 6.
ORGANISM(S): Homo sapiens 
2024-01-31 | E-MTAB-11546 | biostudies-arrayexpress
UnknownNon-specific lipid-transfer proteins: Allergen structure and function, cross-reactivity, sensitization, and epidemiology.
Not available
S-EPMC8129635 | biostudies-literature
UnknownClinical, histological and genetic characterization of reducing body myopathy caused by mutations in FHL1.
Not available
S-EPMC2724920 | biostudies-literature
TranscriptomicsSuppression of NCALD protects against spinal muscular atrophy by restoring impaired endocytosis
Spinal muscular atrophy (SMA) is a common genetic motor neuron (MN) disease caused by low levels of the ubiquitously expressed housekeeping survival motor neuron (SMN) protein, whereas concomitant overexpression of plastin 3 (PLS3) protects from SMA. Here we identify neurocalcin delta (NCALD), a neu...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-58316 | biostudies-arrayexpress
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