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TranscriptomicsExpression of microRNAs and their target mRNAs in hESC-derived cardiomyocyte clusters and in heart tissue_microRNA_data
Parallel transcription profiling of cardiomyocyte clusters derived from human embryonic stem cells. Both mRNA (E-MEXP-2654) and miRNA (this experiment) transcription are measured and fetal and adult heart tissues are included as controls. This experiment was updated on 7th July 2011 to fix incorrect...
ORGANISM(S): Homo sapiens 
2011-03-30 | E-MEXP-2655 | biostudies-arrayexpress
TranscriptomicsMicroRNA array profiling on human pluripotent stem cell-derived cardiomyocytes exposed to doxorubicin
Cardiomyocytes derived from human pluripotent stem cells were exposed to the cardiotoxic drug Doxorubicin in order to assess the utility of this cell system as a model for drug-induced cardiotoxicity. Cells are exposed to different concentrations of doxorubicin for up to 48 hours followed by a 12 da...
ORGANISM(S): Homo sapiens 
2017-10-28 | E-MTAB-6052 | biostudies-arrayexpress
TranscriptomicsRNAseq of iPSC derived cardiomyocytes in response to endothelin-1 as a model for cardiac hypertrophy
The study aims to develop an in vitro model of cardiac hypertrophy using human induced pluripotent stem cells (hPSCs). Human stem cell based disease models are important for reducing the number of animals used in research and to get data the is more relevant to humans. We stimulated hiPSCs derived c...
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-8548 | biostudies-arrayexpress
TranscriptomicsmRNA array profiling on human pluripotent stem cell-derived cardiomyocytes exposed to doxorubicin
Cardiomyocytes derived from human pluripotent stem cells were exposed to the cardiotoxic drug Doxorubicin in order to assess the utility of this cell system as a model for drug-induced cardiotoxicity. Cells are exposed to different concentrations of doxorubicin for up to 48 hours followed by a 12 da...
ORGANISM(S): Homo sapiens 
2017-12-19 | E-MTAB-6045 | biostudies-arrayexpress
TranscriptomicsGlobal expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage
Human pluripotent stem cells (hPSCs) is a promising cell type with capacities of self-renewal and pluripotency, and they can differentiate into in principal any cell types in the body. To fully make use of this unique cell type and develop efficient and reproducible differentiation protocols, more k...
ORGANISM(S): Homo sapiens 
2017-06-08 | E-MTAB-5219 | biostudies-arrayexpress
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