Sort   by:  
 Page size 
ProteomicsSynthetic circular RNA functions as a miR-21 sponge to suppress gastric carcinoma cell proliferation
MicroRNA (miRNA) sponges containing miRNA complementary binding sites constitute a potentially useful strategy for miRNA-inhibition therapeutics in cancer patients. Recently, naturally occurring circular RNAs (circRNAs) have been revealed to function as efficient microRNA sponges. We hypothesized th...
ORGANISM(S): Homo sapiens (Human) 
2018-10-22 | PXD008584 | Pride
Synthetic circular rna  microrna sponge  microrna loss of function  gastric carcinoma  gene therapy 
TranscriptomicsIntroducing synthetic thermostable RNase inhibitors in single-cell RNA-seq
Single-cell RNA-sequencing (scRNAseq) is revolutionizing biomedicine, propelled by advances in methodology, ease of use, and cost reduction of library preparation. Over the past decade, there have been remarkable technical improvements in most aspects of single-cell transcriptomics. Yet, there has b...
ORGANISM(S): Mus musculus 
2024-07-29 | E-MTAB-13873 | biostudies-arrayexpress
GenomicsUse of synthetic circular RNA spike-ins (SynCRS) for normalization of circular RNA sequencing data.
Use of synthetic circular RNA spike-ins (SynCRS) for normalization of circular RNA sequencing data.
PRJNA1089133 | ENA
ProteomicsStructured elements drive circular RNA translation and expand the human proteome, part4
The human genome encodes tens of thousands circular RNAs (circRNAs) whose levels correlate with many disease states. While studies have focused on the non-coding functions of circRNAs, emerging evidence suggests that a handful of circRNAs encode proteins. Translation canonically starts by recognitio...
ORGANISM(S): Homo sapiens (Human) 
2021-08-26 | PXD025203 | Pride
Lc-ms Circular rna Human 
GenomicsStructured elements drive extensive circular RNA translation
Structured elements drive extensive circular RNA translation
PRJNA740184 | ENA
GenomicsDevelopment and comprehensive evaluation of synthetic scarless circular RNAs
Development and comprehensive evaluation of synthetic scarless circular RNAs
PRJNA1200618 | ENA
TranscriptomicsUse of synthetic circular RNA spike-ins (SynCRS) for normalization of circular RNA sequencing data.
High-throughput RNA sequencing is employed to quantify transcript abundance and for the de novo identification of novel transcripts, including a family of alternatively spliced RNA molecules called circular RNAs (circRNAs). However, quantification of circRNAs between sequencing libraries remains cha...
ORGANISM(S): Homo sapiens 
2025-03-20 | GSE261809 | GEO
GenomicsSynthetic circular miR-21 RNA decoys enhance tumor suppressor expression and impair tumor growth in mice (RNA-Seq)
Synthetic circular miR-21 RNA decoys enhance tumor suppressor expression and impair tumor growth in mice (RNA-Seq)
PRJNA625337 | ENA
TranscriptomicsscRNA-seq (3' droplet) of a human and mouse cell line mix (MCF-7, MPC, IMR-5, MDA-MB-231, A549, 4T1, HEK-293, B16, THP-1) labeled with synthetic RNA barcodes
Showcasing the use of synthetic RNA-based barcodes for sample multiplexing in droplet-scRNA-seq. Cell lines were suspended and individually labeled before pooling and 3' droplet scRNA-seq library generation.
ORGANISM(S): mixed sample 
2026-10-09 | E-MTAB-17624 | biostudies-arrayexpress
TranscriptomicsscRNA-seq (Smart-seq3xpress) of a human and mouse cell line mix (4T1, Jurkat, MCF-7, MDA-MB-231, THP-1) labeled with synthetic RNA barcodes
Showcasing the use and recovery of synthetic RNA-based barcodes for sample multiplexing. Cell lines were suspended and individually labeled before pooling, sorting, and Smart-seq3xpress scRNA-seq library generation.
ORGANISM(S): mixed sample 
2026-10-09 | E-MTAB-17623 | biostudies-arrayexpress
Sort   by:  
 Page size