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MetabolomicsInfluence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome
Although the gut microbiome plays important roles in host physiology, health and disease, we lack understanding of the complex interplay between host genetics and early life environment on the microbial and metabolic composition of the gut. We used the genetically diverse Collaborative Cross mouse s...
2016-10-05 | MTBLS345 | MetaboLights
MetabolomicsChemodiverse cell systems responses to UV in an algal sister of land plants

Plant terrestrialization necessitated overcoming a barrage of stressors. Embryophytes (land plants) use an integrated response network to adjust their molecular physiology in response to terrestrial stressors—one of the important stressors is UV irradiance. The zygnematophytes are the closest str...

2026-07-01 | MTBLS8088 | MetaboLights
GenomicsSystems genetics of sleep regulation
Systems genetics of sleep regulation
PRJNA472805 | ENA
TranscriptomicsBrisbane Systems Genetics Study
Brisbane Systems Genetics Study comprises of a total of 862 individuals from 374 families. Families consist of combinations of both MZ and DZ twin pairs, their siblings and for 72 families their parents.
ORGANISM(S): Homo sapiens 
2013-12-11 | GSE53195 | GEO
TranscriptomicsSystems genetics of sleep regulation
We used a systems genetics approach in the BXD genetic reference population of mice and assembled a comprehensive experimental knowledge base comprising a deep ‘sleep-wake’ phenome, central and peripheral transcriptomes, and plasma metabolome data, collected under undisturbed baseline conditions and...
ORGANISM(S): Mus musculus 
2018-06-26 | GSE114845 | GEO
ProteomicsEfficient plasmid-based rescue of T7 RNA polymerase-driven calicivirus reverse genetics systems in mammalian cells using vaccinia virus RNA capping enzymes C4PR_LIV
Calicivirus reverse genetics systems have typically relied on either in vitro transcribed RNA or plasmid-based rescue with enzyme supplementation. Plasmid based calicivirus rescue relies on supplementation with Fowl Pox T7 RNA polymerase which has cost and labour considerations. Here we present a no...
ORGANISM(S): Mesocricetus auratus (Golden hamster) Murine norovirus 
2026-05-13 | PXD074707 | Pride
Rna capping Calicivirus Norovirus Reverse genetics 
TranscriptomicsBrisbane Systems Genetics Study
Brisbane Systems Genetics Study comprises of a total of 862 individuals from 374 families. Families consist of combinations of both MZ and DZ twin pairs, their siblings and for 72 families their parents. Whole blood for expression profiling was collected directly into PAXgene tubes and total RNA was...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-GEOD-53195 | biostudies-arrayexpress
GenomicsSystems Genetics of Lifespan and Senescence in Drosophila melanogaster
Systems Genetics of Lifespan and Senescence in Drosophila melanogaster
PRJNA1295483 | ENA
UnknownSystems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose.
Not available
S-EPMC9060359 | biostudies-literature
ProteomicsReverse Genetics-Rescued Virulent Feline Calicivirus FCV-BJ616 Recapitulates Systemic Disease and Cytokine Storm in Cats
Feline calicivirus (FCV) is a key pathogen causing upper respiratory diseases and oral ulcers in cats, with significant genetic variability. This study aimed to isolate the FCV-BJ616 strain, investigate its pathogenic mechanisms, and provide insights for developing antibody therapies and broad-spect...
ORGANISM(S): Felis chaus 
2026-02-02 | PXD070016 | Pride
Proteomics. Feline calicivirus Reverse genetics of viruses 
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